Prasad Pratibha, Verma Vivek
Department of Neurology, All India Institute of Medical Sciences, Patna, Bihar, India; Former, All India Institute of Medical Science, Deoghar, Jharkhand, India.
Department of Statistics, Assam University, Silchar, Assam, India.
J Family Med Prim Care. 2025 Jun;14(6):2266-2272. doi: 10.4103/jfmpc.jfmpc_1062_24. Epub 2025 Jun 30.
Breakthrough seizures are an essential aspect to consider while treating epilepsy. No study has been done on the precipitating factors for breakthrough seizures in the tribal area of Jharkhand. Hence, awareness regarding the possible precipitating factors of breakthrough seizures is vital to prevent their occurrence.
To determine precipitating factors for breakthrough seizures among patients with epilepsy.
This cross-sectional study was conducted between July 2022 and October 2023. The study included epileptic patients who had been receiving anti-epileptic drugs (AED) for at least 6 months before the survey.
300 patients with epilepsy were included. A total of 46% of epileptic patients had breakthrough seizures. Non-adherence to AED ( < 0.0001); the number of AED ( < 0.0006), duration of treatment ( < 0.05), level of education ( < 0.04), awareness of triggering factors ( < 0.05) and sleep deprivation ( < 0.05) carried the significant association with breakthrough seizures. In contrast, no association was found with gender, occupation, and stress.
Breakthrough seizures are preventable. Hence, there is a need to create awareness of this issue to prevent its occurrence.
突破性癫痫发作是治疗癫痫时需要考虑的一个重要方面。在恰尔肯德邦的部落地区，尚未有关于突破性癫痫发作诱发因素的研究。因此，了解突破性癫痫发作的可能诱发因素对于预防其发生至关重要。
确定癫痫患者突破性癫痫发作的诱发因素。
本横断面研究于2022年7月至2023年10月进行。研究纳入了在调查前至少接受6个月抗癫痫药物（AED）治疗的癫痫患者。
共纳入300例癫痫患者。共有46%的癫痫患者出现突破性癫痫发作。不依从抗癫痫药物治疗（<0.0001）；抗癫痫药物数量（<0.0006）、治疗持续时间（<0.05）、教育程度（<0.04）、对诱发因素的认知（<0.05）和睡眠不足（<0.05）与突破性癫痫发作显著相关。相比之下，未发现与性别、职业和压力有关联。
突破性癫痫发作是可预防的。因此，有必要提高对这个问题的认识以预防其发生。
