Dayapoğlu Nuray, Turan Gülcan Bahcecioglu, Özer Zülfünaz
Faculty of Nursing, Atatürk University, Erzurum, Turkey.
Department of Nursing, Faculty of Health Sciences, Fırat University, Elazığ, Turkey.
Epilepsy Behav. 2021 Oct 28;124:108366. doi: 10.1016/j.yebeh.2021.108366.
This study explored medication adherence and medication beliefs of patients with epilepsy and evaluated the relationship between these two factors.
This descriptive, cross-sectional, correlational study was conducted with 174 patients with epilepsy who were referred to the neurology outpatient clinic of a university hospital in Erzurum, Turkey, between February 10, 2020 and December 30, 2020. The data were collected using the Descriptive Information Form, The eight-item Morisky Medication Adherence Scale (MMAS-8), and the Beliefs about Medicines Questionnaire (BMQ-T).
The mean age of the patients was 33.06 ± 11.94 years, and the mean duration of time since diagnosis was 12.91 ± 10.73 years. In terms of demographic information, 60.3% of the patients were single, 58% had low income or were unemployed, 53.4% had five or more seizures within the last year, 40.8% had focal onset seizures, 69% had no other chronic disease, and 76.4% used more than one medicine. The patients' mean MMAS-8 score was 3.25 ± 2.13. The mean scores for the specific concern subscale was 3.65 ± 0.85, 1.81 ± 0.75 for the specific necessity subscale, 4.19 ± 0.76 for the general overuse subscale, and 3.14 ± 1.41 for the general harm subscale. The regression analysis revealed that general overuse and general harm negatively affected the MMAS-8 total score.
Patients with epilepsy reported low medication adherence and were found to have concerns about the harms and side effects of the medicines they were using; they had negative perceptions of the purpose of medicines; they had high beliefs about the harms of medicines; and they had low beliefs about their personal treatment needs. The patients were generally found to have negative beliefs about medicines, which negatively affected their medication adherence.
本研究探讨癫痫患者的药物依从性和用药信念，并评估这两个因素之间的关系。
本描述性、横断面、相关性研究于2020年2月10日至2020年12月30日期间，对174名转诊至土耳其埃尔祖鲁姆一家大学医院神经科门诊的癫痫患者进行。数据通过描述性信息表、八项Morisky药物依从性量表（MMAS - 8）和药物信念问卷（BMQ - T）收集。
患者的平均年龄为33.06±11.94岁，自诊断以来的平均时间为12.91±10.73年。在人口统计学信息方面，60.3%的患者为单身，58%的患者收入低或失业，53.4%的患者在过去一年中有五次或更多次癫痫发作，40.8%的患者为局灶性发作，69%的患者无其他慢性病，76.4%的患者使用不止一种药物。患者的MMAS - 8平均得分为3.25±2.13。特定关注子量表的平均得分为3.65±0.85，特定必要性子量表为1.81±0.75，一般过度使用子量表为4.19±0.76，一般危害子量表为3.14±1.41。回归分析显示，一般过度使用和一般危害对MMAS - 8总分有负面影响。
癫痫患者报告的药物依从性较低，且对正在使用的药物的危害和副作用存在担忧；他们对药物的目的有负面认知；他们对药物危害的信念较高；他们对个人治疗需求的信念较低。总体而言，患者对药物存在负面信念，这对他们的药物依从性产生了负面影响。
