Kodali Neha, Madu Chikezie O, Lu Yi
Department of Biology, University of Memphis, Memphis, TN 38152, USA.
Department of Biological Sciences, University of Memphis, Memphis, TN 38152, USA.
Curr Issues Mol Biol. 2025 Jul 8;47(7):527. doi: 10.3390/cimb47070527.
Breast cancer is one of the most common forms of cancer in women globally. Phytochemicals are naturally occurring compounds in plants that have been the focus of many research studies for their potential in cancer prevention and treatment. This review will explore the mechanisms certain phytochemicals use to interact with the cellular pathways involved in breast cancer development. Phytochemicals modulate various processes such as apoptosis, cell cycle regulation, angiogenesis, and metastasis to potentially combat breast cancer. This review will also examine different dietary sources of phytochemicals, the potential for integration of phytochemicals into breast cancer therapy, the safety, toxicity, and limitations of phytochemicals, and the future of phytochemicals in the context of breast cancer.
乳腺癌是全球女性中最常见的癌症形式之一。植物化学物质是植物中天然存在的化合物，因其在癌症预防和治疗方面的潜力而成为众多研究的焦点。本综述将探讨某些植物化学物质与乳腺癌发展所涉及的细胞途径相互作用的机制。植物化学物质调节诸如细胞凋亡、细胞周期调控、血管生成和转移等各种过程，以潜在地对抗乳腺癌。本综述还将研究植物化学物质的不同饮食来源、将植物化学物质整合到乳腺癌治疗中的潜力、植物化学物质的安全性、毒性和局限性，以及植物化学物质在乳腺癌背景下的未来。
