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一名新冠病毒肺炎患者出现大量自发性纵隔气肿和广泛皮下气肿

Significant Spontaneous Pneumomediastinum and Extensive Subcutaneous Emphysema in a COVID-19 Patient.

作者信息

Gaspari Arianna, Carrieri Francesca, Villani Matteo, Bertellini Elisabetta

机构信息

Department of Anaesthesia and Intensive Care, Azienda Ospedaliero Universitaria di Modena and Reggio Emilia, Via Del Pozzo 71, 41211 Modena, Italy.

Department Anaesthesia and Intensive Care, Azienda USL Piacenza, Ospedale "Guglielmo da Saliceto" 49, 29121 Piacenza, Italy.

出版信息

Reports (MDPI). 2024 Feb 19;7(1):15. doi: 10.3390/reports7010015.

DOI:10.3390/reports7010015
PMID:40729264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12225390/
Abstract

A 64-year-old man, who had no pre-existing health conditions, was admitted to the intensive care unit due to progressive shortness of breath resulting from COVID-19. Initially, the patient responded to non-invasive mechanical ventilation, which improved his breathing function. However, after six days, his respiratory function worsened significantly, requiring invasive ventilation. Out of nowhere, the person experienced spontaneous pneumomediastinum and extensive subcutaneous emphysema. The next day, a spontaneous pneumothorax occurred and was successfully drained later. It became evident that there was extensive subcutaneous emphysema also. The CT scan of the chest confirmed the presence of spontaneous pneumomediastinum, but it did not have any effect on the patient's hemodynamics. The physicians performed a bronchoscopy and imaging with a contrast medium, which ruled out any lesions to the trachea or esophagus. No other issues related to the problem were identified during the examination. Unfortunately, microscopic bullae of interstitial emphysema, or micro air leaks, are visible when they are an adequate size on computed tomography. Recent literature and studies not available during the case report have shown that if the Macklin effect is detected on the baseline CT scan, it could predict the occurrence of pneumothorax or pneumomediastinum.

摘要

一名64岁的男性,之前没有健康问题,因新型冠状病毒肺炎导致进行性呼吸急促而入住重症监护病房。最初,患者对无创机械通气有反应,呼吸功能得到改善。然而,六天后,他的呼吸功能显著恶化,需要有创通气。毫无征兆地,该患者出现了纵隔气肿和广泛的皮下气肿。第二天,发生了自发性气胸,随后成功进行了引流。显然也存在广泛的皮下气肿。胸部CT扫描证实存在纵隔气肿,但对患者的血流动力学没有任何影响。医生进行了支气管镜检查和造影成像,排除了气管或食管的任何病变。检查期间未发现与该问题相关的其他问题。不幸的是,当间质性肺气肿的微小肺大疱或微小气漏在计算机断层扫描上尺寸足够大时才可见。在病例报告期间没有可获取的最新文献和研究表明,如果在基线CT扫描上检测到麦克林效应,可能预测气胸或纵隔气肿的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/12225390/ea935c3e6903/reports-07-00015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/12225390/08036fd1d4de/reports-07-00015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/12225390/df8d3b27561f/reports-07-00015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/12225390/ea935c3e6903/reports-07-00015-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/12225390/08036fd1d4de/reports-07-00015-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/12225390/df8d3b27561f/reports-07-00015-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2cf/12225390/ea935c3e6903/reports-07-00015-g003.jpg

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本文引用的文献

1
Non-Ventilated Patients with Spontaneous Pneumothorax or Pneumomediastinum Associated with COVID-19: Three-Year Debriefing across Five Pandemic Waves.与COVID-19相关的自发性气胸或纵隔气肿的非通气患者:跨越五个疫情波次的三年总结
J Pers Med. 2023 Oct 15;13(10):1497. doi: 10.3390/jpm13101497.
2
Pneumomediastinum in COVID-19 disease: Clinical review with emphasis on emergency management.新型冠状病毒肺炎相关的纵隔气肿:重点关注急诊处理的临床综述
J Am Coll Emerg Physicians Open. 2023 Apr 10;4(2):e12935. doi: 10.1002/emp2.12935. eCollection 2023 Apr.
3
Clinical use of Macklin-like radiological sign (Macklin effect): A systematic review.
类麦金林放射学征象(麦金林效应)的临床应用:一项系统评价
Respir Med. 2023 Apr-May;210:107178. doi: 10.1016/j.rmed.2023.107178. Epub 2023 Feb 28.
4
Prognosis of Spontaneous Pneumothorax/Pneumomediastinum in Coronavirus Disease 2019: The CoBiF Score.2019冠状病毒病中自发性气胸/纵隔气肿的预后:CoBiF评分
J Clin Med. 2022 Nov 30;11(23):7132. doi: 10.3390/jcm11237132.
5
Incidence and Outcome of Pneumomediastinum in Non-ICU Hospitalized COVID-19 Patients.非 ICU 住院 COVID-19 患者中纵隔气肿的发生率和转归。
Crit Care Med. 2023 Jan 1;51(1):47-56. doi: 10.1097/CCM.0000000000005680. Epub 2022 Oct 5.
6
Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes.急性呼吸窘迫综合征:病因、病理生理学和表型。
Lancet. 2022 Oct 1;400(10358):1145-1156. doi: 10.1016/S0140-6736(22)01485-4. Epub 2022 Sep 4.
7
Barotrauma in COVID 19: Incidence, pathophysiology, and effect on prognosis.新型冠状病毒肺炎中的气压伤:发生率、病理生理学及对预后的影响。
Clin Imaging. 2022 Oct;90:71-77. doi: 10.1016/j.clinimag.2022.06.014. Epub 2022 Jun 28.
8
Macklin effect on baseline chest CT scan accurately predicts barotrauma in COVID-19 patients.基线胸部 CT 扫描上的 Macklin 效应可准确预测 COVID-19 患者的气压伤。
Respir Med. 2022 Jun;197:106853. doi: 10.1016/j.rmed.2022.106853. Epub 2022 Apr 20.
9
Pneumothorax and pneumomediastinum in COVID-19: A case series.COVID-19 相关的气胸和纵隔气肿:病例系列。
Am J Med Sci. 2022 Jun;363(6):548-551. doi: 10.1016/j.amjms.2020.11.024. Epub 2020 Nov 26.
10
Barotrauma in Coronavirus Disease 2019 Patients Undergoing Invasive Mechanical Ventilation: A Systematic Literature Review.新型冠状病毒病患者行有创机械通气时气压伤:系统文献回顾
Crit Care Med. 2022 Mar 1;50(3):491-500. doi: 10.1097/CCM.0000000000005283.