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肌结膜眼球摘除术研究(MES):在尼泊尔一家三级眼科护理中心采用聚甲基丙烯酸甲酯(PMMA)植入物和定制义眼(CMP)的肌结膜眼球摘除术技术的结果。

Myoconjunctival Enucleation Study (MES): Outcome of Myoconjunctival Enucleation Technique with Polymethyl Methacrylate (PMMA) implant and Custom-made prosthesis (CMP) in a tertiary eye care center in Nepal.

作者信息

Gurung Hom Bahadur, Sthapit Purnima Rajkarnikar, Amatya Malita, Bista Dikshya, Adiga Sushant, Poudel Manish, Thapa Raba, Saiju Rohit

机构信息

Department of Oculoplasty and Ocular Oncology, Tilganga Institute of Ophthalmology, Kathmandu, Nepal.

Department of Research and Biostatistics, Tilganga Institute of Ophthalmology, Kathmandu, Nepal.

出版信息

PLoS One. 2025 Jul 29;20(7):e0321703. doi: 10.1371/journal.pone.0321703. eCollection 2025.

Abstract

PURPOSE

To evaluate the average motility of the implant and custom-made prosthesis (CMP) in various gazes following Myoconjunctival enucleation, the surgical duration, and the complications encountered at a tertiary eye hospital.

METHODS

This was a prospective, non-randomized interventional study. Recti muscles were sutured to the fornices before enucleation of the eyeball to minimize surgical time and the need for additional sutures. Thirty-five consecutive patients meeting the inclusion criteria were enrolled. Data on surgery time, complications, and implant/prosthesis motility were recorded and analyzed.

RESULTS

The mean surgical duration was 39.43 ± 4.97 minutes. Mean PMMA implant movement was 2.34 mm in elevation, 2.26 mm in depression, 2.74 mm in abduction, and 2.71 mm in adduction. Custom-made prosthesis (CMP) movement was 2.40 mm in elevation, 2.51 mm in depression, 2.74 mm in abduction, and 2.66 mm in adduction. Complications were minimal: one intraoperative superior rectus slippage, a few cases with early postoperative nausea, vomiting, and headache, all resolved within a week. At six weeks, one suture granuloma and one shallow inferior fornix were noted and managed. Patient satisfaction was high (88.57%), with a mean Likert score of 4.25 ± 0.65 (1 = Very unsatisfied to 5 = Very satisfied). No patient reported dissatisfaction.

CONCLUSION

Myoconjunctival enucleation offers favorable implant and prosthesis motility, a relatively short surgical duration, and minimal complications. High patient satisfaction supports the myoconjunctival enucleation technique as a reliable and well-tolerated surgical option.

摘要

目的

评估在一家三级眼科医院进行肌结膜眼球摘除术后,植入物和定制义眼(CMP)在不同注视方向的平均活动度、手术时长以及所遇到的并发症。

方法

这是一项前瞻性、非随机干预性研究。在摘除眼球前将直肌缝合至穹窿部,以尽量缩短手术时间并减少额外缝合的需求。连续纳入35例符合纳入标准的患者。记录并分析手术时间、并发症以及植入物/义眼活动度的数据。

结果

平均手术时长为39.43 ± 4.97分钟。聚甲基丙烯酸甲酯(PMMA)植入物的平均活动度为:上抬2.34毫米、下转2.26毫米、外展2.74毫米、内收2.71毫米。定制义眼(CMP)的活动度为:上抬2.40毫米、下转2.51毫米、外展2.74毫米、内收2.66毫米。并发症极少:术中1例上直肌滑脱,少数病例术后早期出现恶心、呕吐和头痛,均在一周内缓解。术后六周时,发现并处理了1例缝线肉芽肿和1例下穹窿浅的情况。患者满意度较高(88.57%),平均李克特评分为4.25 ± 0.65(1 = 非常不满意至5 = 非常满意)。没有患者表示不满意。

结论

肌结膜眼球摘除术能使植入物和义眼获得良好的活动度,手术时长相对较短,并发症极少。较高的患者满意度支持肌结膜眼球摘除术作为一种可靠且耐受性良好的手术选择。

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