Karzad Nazila, Taghavi Simin, Mahmoodpoor Ata, Saghaleini Seied Hadi, Safiri Saeid, Hosseinzadeh Pouya
Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Zahra Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Anesthesiology, School of Medicine, Imam Reza Medical Research & Training Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
Eur J Med Res. 2025 Jul 29;30(1):681. doi: 10.1186/s40001-025-02733-x.
This study aims to compare the clinical course of COVID-19 in pregnant versus non-pregnant women aged 15-45 in Tabriz, focusing on disease severity, mortality, and pregnancy outcomes.
A total of 300 women were analyzed, with 150 pregnant and 150 non-pregnant participants. Data collected included demographic information, comorbidities, clinical outcomes, and pregnancy-related complications.
The mean age of pregnant women was 32 years, while non-pregnant women averaged 38 years. Common comorbidities in the pregnant group included gestational diabetes and hypertension. Pregnant women predominantly experienced mild COVID-19 cases, whereas severe cases were more frequent in non-pregnant women; however, these differences were not statistically significant. Both groups had a mortality rate of 4.7%, with seven deaths reported in each cohort. Among pregnant women, 19% experienced preterm births, 6.7% had miscarriages, 3.5% had stillbirths, and 6.7% faced postpartum hemorrhages, with most preterm births being induced.
The findings suggest that pregnancy does not worsen the clinical course of COVID-19, as pregnant women generally exhibit milder symptoms and require fewer intensive care unit admissions compared to their non-pregnant counterparts.
本研究旨在比较大不里士地区15至45岁孕妇与非孕妇感染新型冠状病毒肺炎（COVID-19）的临床病程，重点关注疾病严重程度、死亡率和妊娠结局。
共分析了300名女性，其中150名孕妇和150名非孕妇。收集的数据包括人口统计学信息、合并症、临床结局和妊娠相关并发症。
孕妇的平均年龄为32岁，而非孕妇的平均年龄为38岁。孕妇组常见的合并症包括妊娠期糖尿病和高血压。孕妇主要为轻症COVID-19病例，而非孕妇中重症病例更为常见；然而，这些差异无统计学意义。两组的死亡率均为4.7%，每组均报告有7例死亡。在孕妇中，19%发生早产，6.7%流产，3.5%死产，6.7%出现产后出血，大多数早产为引产。
研究结果表明，妊娠不会使COVID-19的临床病程恶化，因为与非孕妇相比，孕妇通常症状较轻，入住重症监护病房的需求较少。
