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探索神经退行性疾病患者的非药物辅助治疗方法。

Exploring Non-Pharmacologic Adjunctive Therapies for Patients with Neurodegenerative Diseases.

作者信息

Marchiș Maria, Iorga Magdalena

机构信息

Faculty of Psychology and Education Sciences, "Alexandru Ioan Cuza" University, 700554 Iasi, Romania.

Department of Behavioral Sciences, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.

出版信息

Medicina (Kaunas). 2025 Jul 5;61(7):1224. doi: 10.3390/medicina61071224.

DOI:10.3390/medicina61071224
PMID:40731853
Abstract

: Alternative therapies, such as non-invasive neuromodulation techniques, cognitive therapies, virtual reality-based interventions, and psychological support, represent promising approaches for treating and supporting the management plan for patients with neurodegenerative disorders. Recent research has focused on the effectiveness of neuromodulation therapies, as they show improvements in both emotional and cognitive functions in patients with neurodegenerative disorders. : A literature review was conducted by searching Google Scholar, PubMed, Scopus, and Web of Science in February 2025. In total, 20 studies that met the inclusion criteria were considered for the present review, and the studies included were conducted between 2020 and 2025. : Innovative neuromodulation therapies have demonstrated their high potential in the management care plan of neurodegenerative disorders and as non-invasive neuromodulation therapies, both in the emotional manifestations of the patients and in the cognitive ones, with a direct impact on their caregivers' experience. Although research is ongoing, the following preliminary findings are encouraging, suggesting that these methods may complement or even replace certain traditional interventions. : Alternative therapies (non-invasive neuromodulation techniques, cognitive therapies, virtual reality-based interventions, and psychological support) represent promising approaches for treating and supporting the management care plan for neurodegenerative disorders, even in the cases where no other drug-based treatment option can be applied. Each method has its unique advantages, but further studies are needed to create treatment protocols and confirm their long-term effectiveness. Integrating these strategies into personalized management care plans can significantly improve cognitive function and emotional health and increase the quality of life of patients with cognitive and neurodegenerative disorders.

摘要

替代疗法,如非侵入性神经调节技术、认知疗法、基于虚拟现实的干预措施和心理支持,是治疗和支持神经退行性疾病患者管理计划的有前景的方法。最近的研究集中在神经调节疗法的有效性上,因为它们在神经退行性疾病患者的情绪和认知功能方面均显示出改善。

2025年2月,通过搜索谷歌学术、PubMed、Scopus和科学网进行了文献综述。本综述共纳入了20项符合纳入标准的研究,这些研究在2020年至2025年期间开展。

创新的神经调节疗法在神经退行性疾病的管理护理计划中已显示出其巨大潜力,作为非侵入性神经调节疗法,在患者的情绪表现和认知表现方面均有作用,对其护理人员的体验有直接影响。尽管研究仍在进行中,但以下初步发现令人鼓舞,表明这些方法可能补充甚至取代某些传统干预措施。

替代疗法(非侵入性神经调节技术、认知疗法、基于虚拟现实的干预措施和心理支持)是治疗和支持神经退行性疾病管理护理计划的有前景的方法,即使在无法应用其他基于药物的治疗选择的情况下也是如此。每种方法都有其独特优势,但需要进一步研究以制定治疗方案并确认其长期有效性。将这些策略整合到个性化管理护理计划中可显著改善认知功能和情绪健康,并提高认知和神经退行性疾病患者的生活质量。

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