体内血小板聚集的研究。III. 己酮可可碱的作用。
Study of platelet aggregation in vivo. III. Effect of pentoxifylline.
作者信息
Gastpar H, Ambrus J L, Ambrus C M, Spavento P, Weber F J, Thurber L E
出版信息
J Med. 1977;8(3-4):191-7.
PMID:407320
Abstract
Pentoxifylline (Trental) a new vasoactive agent was shown to be a powerful inhibitor of ADP and serotonin induced platelet aggregation of monkey platelets in vivo. A linear dose response curve was demonstrated between 6 and 24 mg/kg of i.v. pentoxifylline.
摘要
己酮可可碱（曲克芦丁）是一种新型血管活性药物，已证明它在体内能有效抑制二磷酸腺苷（ADP）和血清素诱导的猴血小板聚集。静脉注射己酮可可碱6至24毫克/千克时，呈现出线性剂量反应曲线。
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