Roxas Evalyn, Acacio-Claro Paulyn Jean, Lota Maria Margarita, Abeleda Alvin, Dalisay Soledad Natalia, Landicho Madilene, Fujimori Yoshiki, Rosuello Jan Zarlyn, Kaufman Jessica, Danchin Margaret, Belizario Vicente, Vogt Florian
College of Public Health, University of the Philippines Manila, Manila 1000, Philippines.
Unit of Health Sciences, Faculty of Social Sciences, Tampere University, 33520 Tampere, Finland.
Vaccines (Basel). 2025 Jul 1;13(7):719. doi: 10.3390/vaccines13070719.
: The COVID-19 pandemic prompted extensive vaccination efforts globally, yet in the Philippines, many families remained unvaccinated. Caregivers are key decision-makers for family vaccination, but evidence on factors influencing their own vaccine uptake is limited. : A cross-sectional survey of primary caregivers was conducted in low COVID-19 vaccine uptake regions in the Philippines from July to October 2023 using a validated questionnaire. Multivariable logistic regression identified enablers and barriers to vaccine uptake. : Among 775 respondents, 72.3% completed primary vaccination, 3.3% had incomplete vaccination, and 24.4% were unvaccinated. Key factors for vaccination included self, family, and community protection, and the influence of government regulations. Distrust in vaccine safety was the main barrier. Positive associations with vaccine uptake were found for age [30-45 years (aOR = 2.23) and 46-59 years (aOR = 2.84)], education [secondary (aOR = 2.25) and tertiary (aOR = 4.93)], and employment (aOR = 1.99). Confidence in vaccine safety (aOR = 1.92), vaccine effectiveness (aOR = 2.23), and satisfaction with vaccination efforts (aOR = 2.39) were additional enablers. Disagreement with restrictions on the unvaccinated was a barrier (aOR = 0.31). : This study identified multiple factors influencing COVID-19 vaccination among primary caregivers in low uptake areas of the Philippines. Interventions addressing perceptions about vaccine safety and effectiveness, particularly among younger and less educated caregivers, may improve public trust and satisfaction with vaccination efforts.
新冠疫情促使全球广泛开展疫苗接种工作，但在菲律宾，许多家庭仍未接种疫苗。照顾者是家庭疫苗接种的关键决策者，但关于影响他们自身疫苗接种率的因素的证据有限。2023年7月至10月，在菲律宾新冠疫苗接种率较低的地区，使用经过验证的问卷对主要照顾者进行了横断面调查。多变量逻辑回归确定了疫苗接种的促进因素和障碍。在775名受访者中，72.3%完成了基础疫苗接种，3.3%接种不完全，24.4%未接种。接种疫苗的关键因素包括自我、家庭和社区保护以及政府规定的影响。对疫苗安全性的不信任是主要障碍。发现年龄[30 - 45岁（调整后比值比 = 2.23）和46 - 59岁（调整后比值比 = 2.84）]、教育程度[中学（调整后比值比 = 2.25）和大专（调整后比值比 = 4.93）]和就业情况（调整后比值比 = 1.99）与疫苗接种呈正相关。对疫苗安全性的信心（调整后比值比 = 1.92）、疫苗有效性（调整后比值比 = 2.23）以及对疫苗接种工作的满意度（调整后比值比 = 2.39）是其他促进因素。不同意对未接种者的限制是一个障碍（调整后比值比 = 0.31）。这项研究确定了菲律宾疫苗接种率较低地区主要照顾者中影响新冠疫苗接种的多个因素。针对疫苗安全性和有效性认知的干预措施，特别是在年轻和受教育程度较低的照顾者中，可能会提高公众对疫苗接种工作的信任和满意度。
