Larsen Lisbeth Hoejkjaer, Kirk Henrik, Lorentzen Jakob
Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark.
Department of Paediatrics, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Front Neurol. 2025 Jul 15;16:1604061. doi: 10.3389/fneur.2025.1604061. eCollection 2025.
Cerebral palsy (CP) is a neurological disorder that impairs motor control and coordination, often leading to physical and social restrictions in daily activities. This single-arm feasibility study investigates the potential efficacy of virtual moderate- to high-intensity cycling at home among individuals with CP.
Twenty-three individuals with CP () were recruited for a 12-week home-based cycling intervention. The intervention included three weekly sessions, which could be completed either in an online coach-led group setting or independently, along with guidance for additional training. The primary focus was feasibility, addressed by retention, adherence, and safety. Efficacy was primarily evaluated using a functional threshold power test for cycling (FTP), the Timed Up and Go Test (TUG), and the Sit to Stand test (STS), assessed before and after the intervention, and secondly via self-reported questionnaires.
The intervention was demonstrated to be safe and feasible, with no adverse events reported. Retention was high, with only one dropout attributed to mononucleosis. The remaining 22 participants completed the study with a high attendance averaging 3.1 sessions/week [range 2-5]. Improvements were observed in the FTP test (67.2 ± 37.3 W, < 0.001), the TUG test (2.1 ± 1.4 s, < 0.001), and the STS test (3.9 ± 3.3 repetitions, < 0.001) while self-reported fatigue, pain, sleep, well-being, and self-efficacy remained unchanged.
Our findings suggest that virtual cycling at home is a safe and feasible approach to engage in moderate- to high-intensity exercise, enhance physical capacity, and improve functional activity outcomes for individuals with activity limitations.
脑瘫（CP）是一种神经障碍，会损害运动控制和协调能力，常常导致日常活动中的身体和社交受限。这项单臂可行性研究调查了在家中进行虚拟中高强度骑行对脑瘫患者的潜在疗效。
招募了23名脑瘫患者进行为期12周的居家骑行干预。干预包括每周三次课程，可以在在线教练指导的小组环境中完成，也可以独立完成，并提供额外训练的指导。主要关注的是可行性，通过留存率、依从性和安全性来衡量。疗效主要通过干预前后进行的骑行功能阈值功率测试（FTP）、计时起立行走测试（TUG）和坐立测试（STS）来评估，其次通过自我报告问卷进行评估。
该干预被证明是安全可行的，未报告不良事件。留存率很高，只有一名参与者因单核细胞增多症退出。其余22名参与者完成了研究，出勤率很高，平均每周3.1次课程[范围2 - 5]。在FTP测试（67.2±37.3W，<0.001）、TUG测试（2.1±1.4秒，<0.001）和STS测试（3.9±3.3次重复，<0.001）中观察到改善，而自我报告的疲劳、疼痛、睡眠、幸福感和自我效能感保持不变。
我们的研究结果表明，在家中进行虚拟骑行是一种安全可行的方法，可让活动受限的个体进行中高强度运动、增强身体能力并改善功能活动结果。
