Cail Garrett M, Faust Taylor F, Steadman Michael B, Weaver Tony L
Department of Research, Alabama College of Osteopathic Medicine, Dothan, USA.
Plastic and Reconstructive Surgery, Huntsville Hospital, Madison, USA.
Cureus. 2025 Jun 29;17(6):e86961. doi: 10.7759/cureus.86961. eCollection 2025 Jun.
Gynecomastia with associated tissue pigmentation is rarely reported in the literature. We report a rare case of a 39-year-old male with gynecomastia and unexpected pigmentation within breast tissue, presumed to be related to extensive tattoos. This unusual presentation of gynecomastia, combined with visible pigment deposits in breast and lymphatic tissue, introduces a novel intersection between seemingly unrelated findings. Gynecomastia, a benign enlargement of male breast tissue, is typically idiopathic or hormonally driven. In this case, surgery revealed tattoo-like pigmentation within fibroadipose tissue and lymph nodes. Histopathology confirmed the pigment to be consistent with tattoo ink, raising the possibility of migration via lymphatic channels. While tattoo ink complications are well documented in dermatology, this is the first known report of pigment deposition in male breast tissue in the context of gynecomastia. This raises questions about tattoo pigment migration and potential implications in tissue remodeling or pathology.
文献中很少报道伴有相关组织色素沉着的男性乳腺增生症。我们报告了一例罕见病例，一名39岁男性患有男性乳腺增生症，且乳腺组织内出现意外的色素沉着，推测与广泛纹身有关。这种男性乳腺增生症的不寻常表现，加上乳腺和淋巴组织中可见的色素沉着，揭示了看似无关的发现之间的新交集。男性乳腺增生症是男性乳腺组织的良性增生，通常是特发性的或由激素驱动。在这个病例中，手术发现纤维脂肪组织和淋巴结内有类似纹身的色素沉着。组织病理学证实色素与纹身墨水一致，增加了通过淋巴管迁移的可能性。虽然纹身墨水并发症在皮肤病学中有充分记载，但这是已知的首例在男性乳腺增生症背景下男性乳腺组织色素沉着的报告。这引发了关于纹身色素迁移及其在组织重塑或病理学中潜在影响的问题。
