• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

地锦叶提取物对……的抗菌活性及成分分析

Antibacterial activity and compositional analysis of  bunge leaf extract against .

作者信息

Liao Fei, He Jie

机构信息

Guizhou Vocational College of Agriculture, Qingzhen, P.R. China.

出版信息

Vet Med (Praha). 2025 May 28;70(5):166-176. doi: 10.17221/65/2024-VETMED. eCollection 2025 May.

DOI:10.17221/65/2024-VETMED
PMID:40735302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12303035/
Abstract

is a zoonotic pathogen that can cause various diseases in both humans and animals. This experiment evaluates the antibacterial activity of extracts from leaves against , including the minimum inhibitory concentration (MIC), growth curve, and cell membrane integrity assessment, alongside the identification of the extract components by LC-MS. Results demonstrated that the MIC of the -butanol extract from the ethanol extract of  leaves against was 3.125 mg/ml, with a minimum bactericidal concentration (MBC) of 6.25 mg/ml. Over 16 h, the extracts at concentrations of 0.25 MIC, 0.5 MIC, and 1 MIC effectively inhibited growth. The fluorescence staining revealed that the extracts at different concentrations compromised the structural integrity of the cell membrane. The LC-MS analysis identified the principal constituents of the extract as betaine (27.189%), 3,4-dihydroxymandelic acid (16.112%), quercitrin (14.768%), chlorogenic acid (8.778%) and neochlorogenic acid (4.452%). The study indicated that leaf extract has good potential for application in natural antibacterial drugs.

摘要

是一种人畜共患病原体，可在人类和动物中引发多种疾病。本实验评估了叶提取物对的抗菌活性，包括最低抑菌浓度（MIC）、生长曲线和细胞膜完整性评估，同时通过液相色谱 - 质谱联用（LC-MS）鉴定提取物成分。结果表明，叶乙醇提取物的正丁醇提取物对的MIC为3.125毫克/毫升，最低杀菌浓度（MBC）为6.25毫克/毫升。在16小时内，浓度为0.25 MIC、0.5 MIC和1 MIC的提取物有效抑制了的生长。荧光染色显示，不同浓度的提取物破坏了细胞膜的结构完整性。LC-MS分析确定提取物的主要成分是甜菜碱（27.189%）、3,4 - 二羟基扁桃酸（16.112%）、槲皮苷（14.768%）、绿原酸（8.778%）和新绿原酸（4.452%）。该研究表明，叶提取物在天然抗菌药物应用方面具有良好潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/35a542b65532/VETMED-70-05-124065-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/5536c18b25eb/VETMED-70-05-124065-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/869888b9a81e/VETMED-70-05-124065-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/c246b837e09c/VETMED-70-05-124065-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/a597f9632729/VETMED-70-05-124065-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/35a542b65532/VETMED-70-05-124065-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/5536c18b25eb/VETMED-70-05-124065-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/869888b9a81e/VETMED-70-05-124065-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/c246b837e09c/VETMED-70-05-124065-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/a597f9632729/VETMED-70-05-124065-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f98/12303035/35a542b65532/VETMED-70-05-124065-g005.jpg

相似文献

1
Antibacterial activity and compositional analysis of  bunge leaf extract against .地锦叶提取物对……的抗菌活性及成分分析
Vet Med (Praha). 2025 May 28;70(5):166-176. doi: 10.17221/65/2024-VETMED. eCollection 2025 May.
2
Assessing the antibacterial potency of royal jelly: Minimum inhibitory concentration and minimum bactericidal concentration evaluation against and .评估蜂王浆的抗菌效力：针对[具体菌种1]和[具体菌种2]的最低抑菌浓度及最低杀菌浓度评估。
J Conserv Dent Endod. 2025 Jun;28(6):505-509. doi: 10.4103/JCDE.JCDE_682_24. Epub 2025 Jun 2.
3
In-vitro antimicrobial activity of Jatropha variegata Vahl. (Euphorbiaceae) against some pathogenic microbes isolated from clinical samples in Ibb City, Yemen.也门伊卜市麻风树（大戟科）对从临床样本中分离出的一些致病微生物的体外抗菌活性。
Sci Rep. 2025 Jul 8;15(1):24409. doi: 10.1038/s41598-025-10034-w.
4
Phytochemical profile and antimicrobial activity of individual frond extracts of Menisorus pauciflorus, Pteris catoptera, Conniogramme africana and Antrophyum mannianum.少花新月蕨、翅柄凤尾蕨、非洲凤了蕨和万年拟蕨单叶提取物的植物化学特征及抗菌活性
BMC Complement Med Ther. 2025 Jul 12;25(1):262. doi: 10.1186/s12906-025-05003-9.
5
In vitro antibacterial activity of Bersama abyssinica Fresen crude extract against representative Gram-positive and Gram-negative bacterial isolates.比西玛阿比西尼亚 Fresen 粗提物对代表性革兰氏阳性和革兰氏阴性细菌分离株的体外抗菌活性。
Vet Med Sci. 2024 Jul;10(4):e1498. doi: 10.1002/vms3.1498.
6
Antimicrobial activity of Chromolaena odorata crude extracts against Streptococcus suis.飞机草粗提物对猪链球菌的抗菌活性。
Microb Pathog. 2025 Sep;206:107799. doi: 10.1016/j.micpath.2025.107799. Epub 2025 Jun 11.
7
Aqueous leaf extract from exhibits antimicrobial and antibiofilm activity against .来自……的水叶提取物对……具有抗菌和抗生物膜活性。
Future Microbiol. 2025 Aug;20(11):735-742. doi: 10.1080/17460913.2025.2528419. Epub 2025 Jul 24.
8
Evaluation of Antibacterial Activity of Trichilia dregeana Sond. (Meliaceae) Methanolic Extract Against Gram-Positive and Gram-Negative Bacteria.德氏鹧鸪花（楝科）甲醇提取物对革兰氏阳性菌和革兰氏阴性菌的抗菌活性评价
Vet Med Sci. 2025 May;11(3):e70231. doi: 10.1002/vms3.70231.
9
In vitro antimicrobial activity of Thai stick cannabis Hang Kra Rog Phu Phan ( L.), sugar leaves extract against pathogenic bacteria.泰国棒状大麻Hang Kra Rog Phu Phan (L.)糖叶提取物对病原菌的体外抗菌活性。
J Adv Vet Anim Res. 2025 Mar 24;12(1):44-52. doi: 10.5455/javar.2025.l870. eCollection 2025 Mar.
10
Pioneering study of Egyptian Neem and Jojoba extracts with molecular docking combat hospital multidrug resistant bacteria.埃及印楝和霍霍巴提取物与分子对接对抗医院多重耐药细菌的开创性研究。
Braz J Microbiol. 2025 Mar;56(1):425-445. doi: 10.1007/s42770-024-01590-w. Epub 2025 Jan 8.

本文引用的文献

1
Characterization of Staphylococcus aureus isolated from milk samples for their virulence, biofilm, and antimicrobial resistance.从牛奶样本中分离的金黄色葡萄球菌的毒力、生物膜和抗菌耐药性特征。
Sci Rep. 2024 Oct 27;14(1):25635. doi: 10.1038/s41598-024-75076-y.
2
Endophytic Fungus UJ3-2 from : Antibacterial Activity and Mechanism of Action against .内生真菌 UJ3-2 对 : 抗菌活性及作用机制研究。
Molecules. 2024 Oct 13;29(20):4850. doi: 10.3390/molecules29204850.
3
Simple and accurate genomic classification model for distinguishing between human and pig Staphylococcus aureus.
用于区分人源和猪源金黄色葡萄球菌的简单且准确的基因组分类模型。
Commun Biol. 2024 Sep 18;7(1):1171. doi: 10.1038/s42003-024-06883-2.
4
Integrated analysis of metabolome, transcriptome, and bioclimatic factors of Acer truncatum seeds reveals key candidate genes related to unsaturated fatty acid biosynthesis, and potentially optimal production area.对槭树种子的代谢组、转录组和生物气候因素进行综合分析，揭示了与不饱和脂肪酸生物合成相关的关键候选基因，并确定了潜在的最佳生产区域。
BMC Plant Biol. 2024 Apr 16;24(1):284. doi: 10.1186/s12870-024-04936-6.
5
Multi-Host Pathogen -Epidemiology, Drug Resistance and Occurrence in Humans and Animals in Poland.多宿主病原体——波兰人类和动物中的流行病学、耐药性及发生情况
Antibiotics (Basel). 2023 Jun 30;12(7):1137. doi: 10.3390/antibiotics12071137.
6
Antiadhesive and Antibiofilm Effect of Malvidin-3-Glucoside and Malvidin-3-Glucoside/Neochlorogenic Acid Mixtures upon .锦葵色素-3-葡萄糖苷及锦葵色素-3-葡萄糖苷/新绿原酸混合物对……的抗黏附及抗生物膜作用
Metabolites. 2022 Nov 3;12(11):1062. doi: 10.3390/metabo12111062.
7
The antibacterial effect of (L.) R.Br. leaves extract against bacteria associated with peri-implantitis.（L.）R.Br.叶提取物对种植体周围炎相关细菌的抗菌作用。
J Tradit Complement Med. 2022 Aug 3;12(6):556-566. doi: 10.1016/j.jtcme.2022.07.002. eCollection 2022 Nov.
8
A defect in cell wall recycling confers antibiotic resistance and sensitivity in Staphylococcus aureus.细胞壁循环缺陷赋予金黄色葡萄球菌对抗生素的耐药性和敏感性。
J Biol Chem. 2022 Oct;298(10):102473. doi: 10.1016/j.jbc.2022.102473. Epub 2022 Sep 9.
9
Antimicrobial and anti-biofilm activities of chlorogenic acid grafted chitosan against Staphylococcus aureus.绿原酸接枝壳聚糖对金黄色葡萄球菌的抗菌和抗生物膜活性。
Microb Pathog. 2022 Dec;173(Pt A):105748. doi: 10.1016/j.micpath.2022.105748. Epub 2022 Sep 5.
10
Protective effects of chlorogenic acid on inflammatory responses induced by Staphylococcus aureus and milk protein synthesis in bovine mammary epithelial cells.绿原酸对金黄色葡萄球菌诱导的炎症反应及奶牛乳腺上皮细胞乳蛋白合成的保护作用。
Microb Pathog. 2022 Oct;171:105726. doi: 10.1016/j.micpath.2022.105726. Epub 2022 Aug 19.