Wanderley Daniele de Brito, Muratori Filippo, Argollo Nayara, Tolentino Arthur, Miranda Tatiane, Vaz Fernanda, Campos Vania, de Mattos Adriana Marques, Lucena Rita
Universidade Federal da Bahia(UFBA), Salvador, Bahia, Brazil.
Unità Operativa di Psichiatria dello Sviluppo del Dipartimento di Neuroscienze dell'Età Evolutiva dell'IRCCS Stella Maris - Università di Pisa.
Clin Neuropsychiatry. 2025 Jun;22(3):215-228. doi: 10.36131/cnfioritieditore20250305.
This study aims to characterize the developmental, cognitive, and behavioral profiles of children and adolescents with autism spectrum disorder (ASD) without intellectual disability (ID).
A cross-sectional observational study was conducted, including children and adolescents with ASD and an intelligence quotient (IQ) of 75 or higher. Parents completed the CBCL, and SNAP-IV 26 Parent Rating Scale to assess developmental milestones, cognitive abilities, and behavioral symptoms.
The study included 74 participants, with a mean age of 9.8 ± 2.9 years, of whom 64 (86.5%) were male. Mothers and fathers had a mean age of 33.4 ± 5.5 and 30.2 ± 5.7 years, respectively, with 64.9% of mothers and 47.9% of fathers having completed higher education. Generalized anxiety and depression were the most frequent psychiatric histories reported by parents. Median IQ scores were: total 100 (88-113), verbal 102 (85-117), and performance 97 (90-108). While 82.5% of children spoke their first words before 24 months, only 40% were able to form phrases by age 2. Prosody, pragmatic difficulties, and echolalia were present in over 40% of cases. Moderate or severe symptoms of inattention, hyperactivity, and oppositional behaviors were observed in 33.8%, 16.2%, and 16.2% of participants, respectively. Internalizing symptoms were present in 27%, and externalizing symptoms in 15% of the sample. Learning challenges included difficulties with text interpretation (31%), text production (24%), reading, and math (19% each).
Children and adolescents with ASD without ID exhibit significant behavioral and cognitive challenges, including language delays, inattention, internalizing symptoms, and learning difficulties. These findings emphasize the need for targeted educational and therapeutic strategies to address their unique developmental and behavioral profiles.
本研究旨在描述无智力障碍(ID)的自闭症谱系障碍(ASD)儿童及青少年的发育、认知和行为特征。
开展了一项横断面观察性研究,纳入了ASD且智商(IQ)为75或更高的儿童及青少年。家长完成儿童行为量表(CBCL)和SNAP-IV 26项家长评定量表,以评估发育里程碑、认知能力和行为症状。
该研究纳入了74名参与者,平均年龄为9.8±2.9岁,其中64名(86.5%)为男性。母亲和父亲的平均年龄分别为33.4±5.5岁和30.2±5.7岁,64.9%的母亲和47.9%的父亲完成了高等教育。广泛性焦虑和抑郁是家长报告的最常见精神病史。IQ中位数得分分别为:总分100(88 - 113)、语言102(85 - 117)和操作97(90 - 108)。虽然82.5%的儿童在24个月前说出了第一个单词,但只有40%的儿童在2岁时能够说出短语。超过40%的病例存在韵律、语用困难和模仿言语。分别有33.8%、16.2%和16.2%的参与者出现中度或重度注意力不集中、多动和对立行为症状。27%的样本存在内化症状,15%存在外化症状。学习方面的挑战包括文本理解困难(31%)、文本生成困难(24%)、阅读和数学困难(各19%)。
无ID的ASD儿童及青少年表现出显著的行为和认知挑战,包括语言发育迟缓、注意力不集中、内化症状和学习困难。这些发现强调了需要有针对性的教育和治疗策略来应对他们独特的发育和行为特征。