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慢性肾病患者的不同类型贫血

Different types of anemia in patients with chronic kidney disease.

作者信息

Shah Syed Ahmad, Bilal Muhammad, Khan Yaseen, Fareezuddin Miaz

机构信息

Syed Ahmad Shah, MBBS, FCPS. Medical Officer, Lady Reading Hospital, Peshawar, Pakistan.

Muhammad Bilal, MBBS, FCPS, MRCPI, FRCPI, CHPE, CHR. Associate Professor, Medicine, Lady Reading Hospital, Peshawar, Pakistan.

出版信息

Pak J Med Sci. 2025 Jul;41(7):2017-2022. doi: 10.12669/pjms.41.7.11398.

DOI:10.12669/pjms.41.7.11398
PMID:40735588
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12302120/
Abstract

OBJECTIVE

This study aimed to assess the prevalence of different anemia patterns in CKD patients.

METHODS

This cross-sectional study was carried out at the Outpatient Department of General Medicine, Lady Reading Hospital, Peshawar from 1st July to 31 December, 2023. Non-probability consecutive sampling was employed. Demographic data was collected and anemia was evaluated through Complete Blood Counts for each participant. Statistical analysis was performed using SPSS version 23.

RESULTS

The study included a cohort of 209 participants with an average age of 40.78 ± 6.37 years and a mean BMI of 26.12 ± 4.11 kg/m². Among the participants, 72.2% were male and 27.8% were female. The most common CKD patterns were normocytic (41.1%), hypochromic microcytic (32.5%), and hypochromic macrocytic (26.3%). The majority of participants (78.9%) had experienced CKD for over one year. No significant association was found between the types of anemia in CKD and gender, underlying cause of CKD, age, BMI, or duration of the disease.

CONCLUSION

Our study highlights the prevalence of various types of anemia in chronic kidney disease (CKD) among participants, with normocytic anemia emerging as the most prevalent, followed by hypochromic and hyperchromic patterns. Additionally, longitudinal studies could provide insights into the progression and management of anemia in CKD patients over time.

摘要

目的

本研究旨在评估慢性肾脏病(CKD)患者中不同贫血模式的患病率。

方法

本横断面研究于2023年7月1日至12月31日在白沙瓦市莱迪·雷丁医院综合内科门诊进行。采用非概率连续抽样。收集人口统计学数据,并通过对每位参与者进行全血细胞计数来评估贫血情况。使用SPSS 23版进行统计分析。

结果

该研究纳入了209名参与者,平均年龄为40.78±6.37岁,平均体重指数为26.12±4.11kg/m²。参与者中,7男占2.2%,女性占27.8%。最常见的CKD模式为正细胞性(41.1%)、低色素小细胞性(32.5%)和低色素大细胞性(26.3%)。大多数参与者(78.9%)的CKD病程超过一年。未发现CKD患者贫血类型与性别、CKD潜在病因、年龄、体重指数或疾病持续时间之间存在显著关联。

结论

我们的研究突出了参与者中慢性肾脏病(CKD)患者各种类型贫血的患病率,正细胞性贫血最为普遍,其次是低色素性和高色素性模式。此外,纵向研究可以为CKD患者贫血随时间的进展及管理提供见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e748/12302120/f5d6add3b0ad/PJMS-41-2017-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e748/12302120/f5d6add3b0ad/PJMS-41-2017-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e748/12302120/f5d6add3b0ad/PJMS-41-2017-g001.jpg

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Association between Body Mass Index and Renal Outcomes Modified by Chronic Kidney Disease and Anemia: The Obesity Paradox for Renal Outcomes.体重指数与慢性肾脏病和贫血所改变的肾脏结局之间的关联:肾脏结局的肥胖悖论
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