Nunez E A, Payette R, Gershon M D
Anat Rec. 1985 Oct;213(2):176-81. doi: 10.1002/ar.1092130209.
The ultrastructure of the two types of cells, ciliated and microvillous, lining the wall of the bat pituitary cleft was examined at different periods during the annual life cycle. Ciliated lining cells remained unchanged in structure throughout the yearly activity cycle. In contrast, microvillous lining cells exhibited striking cyclic morphological changes. Throughout the active phase of the life cycle and during most of the hibernating period, the structure of microvillous cells is unchanged. However, toward the end of hibernation, the cells produce and store large numbers of round to ovoid dense secretory granules. Just prior to arousal, the microvillous cells are packed with secretory granules. At arousal, the cells undergo marked degranulation; the granules appear to be discharged into the lumen of the cleft. Degranulation is followed by a period of proliferation of rough endoplasmic reticulum, the cavity of which is often filled with large paracrystalline inclusions. Within 1 month, microvillous cells return to a resting state and are devoid of secretory granules.
在蝙蝠垂体裂壁上，对纤毛细胞和微绒毛细胞这两种类型的细胞超微结构，在其年度生命周期的不同阶段进行了检查。在全年活动周期中，纤毛衬里细胞结构保持不变。相比之下，微绒毛衬里细胞呈现出显著的周期性形态变化。在生命周期的活跃阶段以及大部分冬眠期，微绒毛细胞的结构没有变化。然而，在冬眠即将结束时，这些细胞产生并储存大量圆形至卵形的致密分泌颗粒。就在苏醒前，微绒毛细胞充满了分泌颗粒。在苏醒时，细胞经历明显的脱颗粒过程；颗粒似乎被排放到裂腔中。脱颗粒之后是粗面内质网增殖期，其腔中常常充满大的副晶状内含物。在1个月内，微绒毛细胞恢复到静止状态，且没有分泌颗粒。
