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Comment on 'Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting-Induced Proteolysis' by Espino-Guarch et al.

作者信息

Li Jinglin, Peng Jiachen

机构信息

Affiliated Hospital of Zunyi Medical University, Zunyi, China.

Zunyi Medical University, Zunyi, China.

出版信息

J Cachexia Sarcopenia Muscle. 2025 Aug;16(4):e70037. doi: 10.1002/jcsm.70037.

DOI:10.1002/jcsm.70037
PMID:40735807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12308211/
Abstract
摘要

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本文引用的文献

1
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting-Induced Proteolysis.LAT2转运体的消融导致肌肉内谷氨酰胺积累并抑制禁食诱导的蛋白水解。
J Cachexia Sarcopenia Muscle. 2025 Jun;16(3):e13847. doi: 10.1002/jcsm.13847.
2
Amino acid transporters in the regulation of insulin secretion and signalling.氨基酸转运体在胰岛素分泌和信号转导中的调节作用。
Biochem Soc Trans. 2019 Apr 30;47(2):571-590. doi: 10.1042/BST20180250. Epub 2019 Apr 1.
3
Exercise-Induced Changes in Visceral Adipose Tissue Mass Are Regulated by IL-6 Signaling: A Randomized Controlled Trial.运动诱导的内脏脂肪组织质量变化受 IL-6 信号调节:一项随机对照试验。
Cell Metab. 2019 Apr 2;29(4):844-855.e3. doi: 10.1016/j.cmet.2018.12.007. Epub 2018 Dec 27.
4
Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway.亚精胺与运动相结合,通过增强自噬并经由AMPK-FOXO3a信号通路减少细胞凋亡,挽救D-半乳糖诱导的衰老大鼠的骨骼肌萎缩。
Oncotarget. 2017 Mar 14;8(11):17475-17490. doi: 10.18632/oncotarget.15728.
5
Mitochondrial Quality Control and Muscle Mass Maintenance.线粒体质量控制与肌肉质量维持
Front Physiol. 2016 Jan 12;6:422. doi: 10.3389/fphys.2015.00422. eCollection 2015.
6
mTOR: a pharmacologic target for autophagy regulation.mTOR:自噬调节的药理学靶点。
J Clin Invest. 2015 Jan;125(1):25-32. doi: 10.1172/JCI73939. Epub 2015 Jan 2.
7
FGF21 is an endocrine signal of protein restriction.成纤维细胞生长因子21是蛋白质限制的一种内分泌信号。
J Clin Invest. 2014 Sep;124(9):3913-22. doi: 10.1172/JCI74915. Epub 2014 Aug 18.
8
STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.STAT3 在骨骼肌中的激活将肌肉减少与癌症恶病质的急性期反应联系起来。
PLoS One. 2011;6(7):e22538. doi: 10.1371/journal.pone.0022538. Epub 2011 Jul 20.
9
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.Ragulator-Rag 复合物将 mTORC1 靶向到溶酶体表面,并且对于其被氨基酸激活是必需的。
Cell. 2010 Apr 16;141(2):290-303. doi: 10.1016/j.cell.2010.02.024. Epub 2010 Apr 8.
10
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.在生命后期喂食雷帕霉素可延长基因异质小鼠的寿命。
Nature. 2009 Jul 16;460(7253):392-5. doi: 10.1038/nature08221. Epub 2009 Jul 8.