Cole P, Haight J S, Love L, Oprysk D
Am Rev Respir Dis. 1985 Dec;132(6):1229-32. doi: 10.1164/arrd.1985.132.6.1229.
This investigation was undertaken to demonstrate the contributions of dynamic vestibular and mucosal components to nasal air-flow resistance in healthy human adults. The studies were made by video recording of alar movement, electromyography of alar muscle activity, and by computer-assisted plethysmographic measurement of nasal air-flow resistance. Inspiratory approximation of the alae toward the septum from their expiratory position averaged only 0.6 mm at the high nasal ventilation of 35 L/min; it was less at lower ventilation and absent during voluntary mouth breathing. Inspiratory electromyographic activity also was directly related to the extent of nasal ventilation and was absent during voluntary mouth breathing. The activity was consistent with phasic muscular restraint of vestibular compliance with inspiratory transnasal pressures. Physiologic nasal air-flow resistance changes associated with posture, the nasal cycle, exercise, and hyperventilation persisted despite immobilization of the alae by splinting the vestibule widely open. These changes were abolished by topical decongestant, even in the unsplinted nose, and are therefore vascular.
本研究旨在阐明动态前庭和黏膜成分对健康成年人类鼻气流阻力的作用。通过对鼻翼运动进行视频记录、对鼻翼肌肉活动进行肌电图检查以及通过计算机辅助体积描记法测量鼻气流阻力来开展这些研究。在35升/分钟的高鼻通气量时，鼻翼从呼气位置向鼻中隔的吸气性靠近平均仅为0.6毫米；在较低通气量时该距离更小，而在主动经口呼吸时则不存在这种情况。吸气肌电图活动也与鼻通气程度直接相关，在主动经口呼吸时不存在。该活动与前庭顺应性随吸气经鼻压力的阶段性肌肉抑制一致。尽管通过将前庭广泛撑开固定鼻翼，但与姿势、鼻周期、运动和过度通气相关的生理性鼻气流阻力变化仍然存在。即使在未固定的鼻腔中，这些变化也可被局部减充血剂消除，因此是血管性的。
