Strohl K P, O'Cain C F, Slutsky A S
J Appl Physiol Respir Environ Exerc Physiol. 1982 Jun;52(6):1432-7. doi: 10.1152/jappl.1982.52.6.1432.
To investigate the effect of alae nasi (AN) activation on nasal resistance, we monitored AN electromyographic (EMG) activity in 17 healthy subjects using surface electrodes placed on either side of the external nares and measured inspiratory nasal resistance utilizing the method of posterior rhinometry. With CO2 inhalation (6 subj), AN EMG activity increased as nasal resistance fell 23 +/- 5% (P less than 0.01). In the same subjects, voluntary flaring of the external nares also increased AN EMG and decreased nasal resistance by 29 +/- 5% (P less than 0.01). Nasal resistance was altered by nasal flaring and CO2 inhalation even after administration of a topical nasal vasoconstrictive spray (8 subj). In six subjects, voluntary nasal flaring or inhibition with the mouth closed produced a 21 +/- 12% change (P less than 0.01) in total airway resistance as measured by body plethysmography. We conclude that activation of the alae nasi will decrease nasal and total airway resistance during voluntary nasal flaring and during CO2 inhalation and thus should be considered in any studies of upper airway resistance.
为研究鼻翼激活对鼻阻力的影响，我们使用置于双侧鼻孔外侧的表面电极监测了17名健康受试者的鼻翼肌电图（EMG）活动，并采用后鼻测压法测量了吸气鼻阻力。在吸入二氧化碳的情况下（6名受试者），随着鼻阻力下降23±5%（P<0.01），鼻翼EMG活动增加。在同一受试者中，主动扩张鼻孔也会增加鼻翼EMG，并使鼻阻力降低29±5%（P<0.01）。即使在使用局部鼻血管收缩喷雾剂后（8名受试者），鼻翼扩张和吸入二氧化碳仍会改变鼻阻力。在6名受试者中，主动鼻翼扩张或闭嘴抑制会使通过体容积描记法测量的总气道阻力产生21±12%的变化（P<0.01）。我们得出结论，在主动鼻翼扩张和吸入二氧化碳期间，鼻翼激活会降低鼻阻力和总气道阻力，因此在任何关于上气道阻力的研究中都应予以考虑。
