Wang Yannan, Wang Hexi, Fang Yue
Cadre's Ward, General Hospital of Northern Theater Command, No.83,Wenhua Road,Shenhe District, Shenyang, 110016, China.
Aging Clin Exp Res. 2025 Jul 30;37(1):237. doi: 10.1007/s40520-025-03145-x.
This study aims to analyze the global impact of population ageing on stroke-related disability-adjusted life years (DALYs) from 1990 to 2021.
Decomposition analysis was conducted using Global Burden of Disease (GBD) data to isolate the contributions of population size, ageing, and age-specific stroke rates to stroke-related DALYs.
Population ageing was found to be the dominant driver of stroke-related DALYs globally. From 1990 to 2021, population ageing contributed to an increase of 55.24 million stroke-related DALYs. The greatest impact was observed in Middle-SDI regions, where stroke-related DALYs attributable to population ageing rose significantly. Among the GBD regions, East Asia had the highest contribution to stroke-related DALYs attributed to population ageing for males (100.41%), while High-income Asia Pacific recorded the highest for females (97.49%). In stroke subtypes, ischemic stroke was the most significantly affected by population ageing, while subarachnoid hemorrhage (SAH) was the least affected.
Population ageing is a dominant driver of the growing global stroke burden, necessitating targeted public health interventions for ageing populations.
本研究旨在分析1990年至2021年全球人口老龄化对中风相关伤残调整生命年(DALYs)的影响。
利用全球疾病负担(GBD)数据进行分解分析,以确定人口规模、老龄化和特定年龄中风发病率对中风相关DALYs的贡献。
全球范围内,人口老龄化是中风相关DALYs的主要驱动因素。1990年至2021年,人口老龄化导致中风相关DALYs增加了5524万。在中社会人口指数(SDI)地区观察到的影响最大,其中人口老龄化导致的中风相关DALYs显著上升。在GBD各地区中,东亚男性因人口老龄化导致的中风相关DALYs贡献最高(100.41%),而高收入亚太地区女性的这一比例最高(97.49%)。在中风亚型中,缺血性中风受人口老龄化影响最为显著,而蛛网膜下腔出血(SAH)受影响最小。
人口老龄化是全球中风负担不断增加的主要驱动因素,因此有必要针对老年人群采取有针对性的公共卫生干预措施。