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人口老龄化对中风相关伤残调整生命年的影响:一项全球分解分析。

Impact of population ageing on stroke-related disability-adjusted life years: a global decomposition analysis.

作者信息

Wang Yannan, Wang Hexi, Fang Yue

机构信息

Cadre's Ward, General Hospital of Northern Theater Command, No.83,Wenhua Road,Shenhe District, Shenyang, 110016, China.

出版信息

Aging Clin Exp Res. 2025 Jul 30;37(1):237. doi: 10.1007/s40520-025-03145-x.

Abstract

BACKGROUND

This study aims to analyze the global impact of population ageing on stroke-related disability-adjusted life years (DALYs) from 1990 to 2021.

METHODS

Decomposition analysis was conducted using Global Burden of Disease (GBD) data to isolate the contributions of population size, ageing, and age-specific stroke rates to stroke-related DALYs.

RESULTS

Population ageing was found to be the dominant driver of stroke-related DALYs globally. From 1990 to 2021, population ageing contributed to an increase of 55.24 million stroke-related DALYs. The greatest impact was observed in Middle-SDI regions, where stroke-related DALYs attributable to population ageing rose significantly. Among the GBD regions, East Asia had the highest contribution to stroke-related DALYs attributed to population ageing for males (100.41%), while High-income Asia Pacific recorded the highest for females (97.49%). In stroke subtypes, ischemic stroke was the most significantly affected by population ageing, while subarachnoid hemorrhage (SAH) was the least affected.

CONCLUSIONS

Population ageing is a dominant driver of the growing global stroke burden, necessitating targeted public health interventions for ageing populations.

摘要

背景

本研究旨在分析1990年至2021年全球人口老龄化对中风相关伤残调整生命年(DALYs)的影响。

方法

利用全球疾病负担(GBD)数据进行分解分析,以确定人口规模、老龄化和特定年龄中风发病率对中风相关DALYs的贡献。

结果

全球范围内,人口老龄化是中风相关DALYs的主要驱动因素。1990年至2021年,人口老龄化导致中风相关DALYs增加了5524万。在中社会人口指数(SDI)地区观察到的影响最大,其中人口老龄化导致的中风相关DALYs显著上升。在GBD各地区中,东亚男性因人口老龄化导致的中风相关DALYs贡献最高(100.41%),而高收入亚太地区女性的这一比例最高(97.49%)。在中风亚型中,缺血性中风受人口老龄化影响最为显著,而蛛网膜下腔出血(SAH)受影响最小。

结论

人口老龄化是全球中风负担不断增加的主要驱动因素,因此有必要针对老年人群采取有针对性的公共卫生干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd49/12310854/529dada09d7d/40520_2025_3145_Fig1_HTML.jpg

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