Garnier R, Carlier P, Hoffelt J, Savidan A
Ann Med Interne (Paris). 1985;136(2):125-8.
Five cases of acute accidental poisoning with White Hellebore are reported. All cases occurred several minutes after the ingestion of home-made gentian wine. The clinical signs were nausea, vomiting, abdominal pain, hypotension and bradycardia. The initial ECG showed sinus bradycardia in 4 cases. In one patient, complete atrioventricular block with an ectopic atrial bradycardia and an intermittent idioventricular rhythm was recorded. Symptomatic treatment and/or atropine led to recovery within a few hours. These symptoms suggested poisoning with a veratrum alkaloid. The White Hellebore (Veratrum Album L.) and the Yellow Gentian (Gentiana Lutea L.) often grow side by side in the fields; it is easy to confuse the two plants before they flower if one is not a botanist. Each gentian wine was analysed by thin layer chromatography and chemical ionisation spectrometry. All the wines contained Veratrum alkaloids.
报告了5例误食白藜芦导致的急性意外中毒病例。所有病例均在饮用自制龙胆酒后几分钟内发生。临床症状为恶心、呕吐、腹痛、低血压和心动过缓。最初的心电图显示4例为窦性心动过缓。1例患者记录到完全性房室传导阻滞伴异位房性心动过缓和间歇性室性自主心律。对症治疗和/或使用阿托品后,患者在数小时内康复。这些症状提示藜芦生物碱中毒。白藜芦(Veratrum Album L.)和黄龙胆(Gentiana Lutea L.)在田间常并排生长;如果不是植物学家,在它们开花之前很容易将这两种植物混淆。对每瓶龙胆酒进行了薄层色谱分析和化学电离光谱分析。所有的酒中都含有藜芦生物碱。