Schaefer S, Freeman F, Finitzo T, Close L, Cannito M, Ross E, Reisch J, Maravilla K
Ann Otol Rhinol Laryngol. 1985 Nov-Dec;94(6 Pt 1):595-601. doi: 10.1177/000348948509400615.
A sample of 19 spasmodic dysphonia (SD) patients was selected from a larger population of such patients to undergo magnetic resonance imaging (MRI), auditory brain stem response (ABR) testing, speech analysis, and extensive physical examination. Six patients had abnormal spin-echo MRI findings, ranging from infarcts within the basal ganglia to demyelinating lesions within the supralateral angles of the lateral ventricles. A weakly positive correlation was noted between the abnormal MRI findings and an abnormal ABR. The lack of a significant correlation between the MRI findings and other predictors of brain stem and midbrain disease, and the current spatial resolution limitations of MRI, suggest that we are visualizing the associated lesions rather than the actual foci of SD. The range of MRI findings is consistent with the concept that SD is a voice disorder in a heterogeneous patient population.
从大量痉挛性发声障碍（SD）患者中选取了19名患者样本，进行磁共振成像（MRI）、听觉脑干反应（ABR）测试、言语分析和全面的体格检查。6名患者的自旋回波MRI检查结果异常，范围从基底节梗死到侧脑室上外侧角的脱髓鞘病变。MRI异常结果与ABR异常之间存在弱正相关。MRI结果与脑干和中脑疾病的其他预测指标之间缺乏显著相关性，以及MRI目前的空间分辨率限制，表明我们看到的是相关病变而非SD的实际病灶。MRI检查结果的范围与SD是异质性患者群体中的一种语音障碍这一概念相符。
