埃里莫佛亭C向PR毒素的化学转化。
Chemical transformation of eremofortin C into PR toxin.
作者信息
Li S Y, Chang S C, Wei R D
出版信息
Appl Environ Microbiol. 1985 Sep;50(3):729-31. doi: 10.1128/aem.50.3.729-731.1985.
Abstract
The natural products of both eremofortin C (EC) and PR toxin are secondary metabolites of Penicillium roqueforti. Because the chemical structures of EC and PR toxin are closely related to each other and differ only by a hydroxyl functional group in EC and an aldehyde functional group in PR toxin at the C-12 position, the chemical transformation of EC into PR toxin was investigated. Oxidation with a chromic anhydride-pyridine complex was found to be the most satisfactory method.
摘要
蠕孢菌素C（EC）和PR毒素的天然产物均为罗克福青霉的次生代谢产物。由于EC和PR毒素的化学结构彼此密切相关，仅在C-12位上，EC有一个羟基官能团而PR毒素有一个醛基官能团，因此对EC向PR毒素的化学转化进行了研究。发现用铬酸酐-吡啶络合物氧化是最令人满意的方法。
相似文献
1
Chemical transformation of eremofortin C into PR toxin.埃里莫佛亭C向PR毒素的化学转化。
Appl Environ Microbiol. 1985 Sep;50(3):729-31. doi: 10.1128/aem.50.3.729-731.1985.
2
Factors affecting the production of eremofortin C and PR toxin in Penicillium roqueforti.影响罗克福青霉中埃里莫福汀C和PR毒素产生的因素。
Appl Environ Microbiol. 1991 Sep;57(9):2581-5. doi: 10.1128/aem.57.9.2581-2585.1991.
3
Potentiation effect of corn extract on the production of eremofortin C, EC oxidase, and PR toxin by Penicillium roqueforti.玉米提取物对罗克福青霉产生埃雷莫菌素C、EC氧化酶和PR毒素的增强作用。
Proc Natl Sci Counc Repub China B. 1991 Jul;15(3):153-9.
4
Volatile sesquiterpene hydrocarbons characteristic for Penicillium roqueforti strains producing PR toxin.产生PR毒素的罗克福特青霉菌株所特有的挥发性倍半萜碳氢化合物。
J Agric Food Chem. 2002 Oct 23;50(22):6569-74. doi: 10.1021/jf020311o.
5
Eremofortin C.A new metabolite obtained from penicillium roqueforti cultures and from biotransformation of PR toxin.岩青霉素C。一种从罗克福青霉培养物以及PR毒素生物转化中获得的新代谢产物。
J Org Chem. 1977 Jul 22;42(15):2632-4. doi: 10.1021/jo00435a023.
6
Isolation and Some Properties of the Enzyme That Transforms Eremofortin C to PR Toxin.异戊烯基转移酶 C 向 PR 毒素转化的酶的分离与性质。
Appl Environ Microbiol. 1985 Jun;49(6):1455-60. doi: 10.1128/aem.49.6.1455-1460.1985.
7
Secondary metabolites resulting from degradation of PR toxin by Penicillium roqueforti.由罗克福青霉降解PR毒素产生的次生代谢产物。
Appl Environ Microbiol. 1993 Apr;59(4):981-6. doi: 10.1128/aem.59.4.981-986.1993.
8
Influence of octanoic acid addition to medium on some volatile compounds and PR-toxin biosynthesis by Penicillium roqueforti.向培养基中添加辛酸对罗克福青霉某些挥发性化合物及PR毒素生物合成的影响。
Lett Appl Microbiol. 2002;35(1):37-41. doi: 10.1046/j.1472-765x.2002.01125.x.
9
Penicillium roqueforti PR toxin gene cluster characterization.罗克福特青霉PR毒素基因簇的特征分析。
Appl Microbiol Biotechnol. 2017 Mar;101(5):2043-2056. doi: 10.1007/s00253-016-7995-5. Epub 2016 Dec 5.
10
Identification of intermediates in the biosynthesis of PR toxin by Penicillium roqueforti.鉴定罗伊氏乳杆菌生物合成 PR 毒素的中间产物。
Angew Chem Int Ed Engl. 2015 Oct 5;54(41):12167-70. doi: 10.1002/anie.201506128. Epub 2015 Aug 12.
本文引用的文献
1
Production of Eremofortins A, B, and C Relative to Formation of PR Toxin by Penicillium roqueforti.青霉属产埃氏菌素 A、B、C 与罗克福青霉产生 PR 毒素的关系。
Appl Environ Microbiol. 1980 Apr;39(4):770-6. doi: 10.1128/aem.39.4.770-776.1980.
2
Acute toxicity of PR toxin, a mycotoxin from Penicillium roqueforti.罗克福青霉产生的霉菌毒素PR毒素的急性毒性
Toxicon. 1982;20(2):433-41. doi: 10.1016/0041-0101(82)90006-x.
3
Isolation and partial characterization of a mycotoxin from Penicillium roqueforti.从罗克福青霉中分离出一种霉菌毒素并进行部分特性鉴定。
Appl Microbiol. 1973 Jan;25(1):111-4. doi: 10.1128/am.25.1.111-114.1973.
4
Relationships between the chemical structure and the biological properties of some eremophilane compounds related to PR toxin.
Chem Biol Interact. 1977 May;17(2):185-92. doi: 10.1016/0009-2797(77)90083-7.
5
Eremofortin C.A new metabolite obtained from penicillium roqueforti cultures and from biotransformation of PR toxin.岩青霉素C。一种从罗克福青霉培养物以及PR毒素生物转化中获得的新代谢产物。
J Org Chem. 1977 Jul 22;42(15):2632-4. doi: 10.1021/jo00435a023.
6
Resolution of Penicillium roqueforti toxin and eremofortins A, B, and C by high-performance liquid chromatography.利用高效液相色谱法分离罗克福青霉毒素及伊氏菌素A、B和C
Appl Environ Microbiol. 1979 Jun;37(6):1059-62. doi: 10.1128/aem.37.6.1059-1062.1979.
7
Genetic effects of PR toxin in eukaryotic microorganisms.PR毒素对真核微生物的遗传效应。
Environ Mutagen. 1979;1(1):45-53. doi: 10.1002/em.2860010111.
8
PR toxin production in different Penicillium roqueforti strains.不同罗克福青霉菌株中PR毒素的产生情况。
Appl Environ Microbiol. 1978 Apr;35(4):797-9. doi: 10.1128/aem.35.4.797-799.1978.
9
In vitro metabolism of penicillium roqueforti toxin (PRT) and a structurally related compound, eremofortin A, by rat liver.
Toxicology. 1977 Oct;8(2):205-12. doi: 10.1016/0300-483x(77)90009-9.
Zotero 插件