Li Jiang-Bo, Rong Wei
Department of Psychosomatics, Jianyang People's Hospital, Jianyang 641400, Sichuan Province, China.
Department of Clinical Psychology, Wuhu Hospital Affiliated to East China Normal University, Wuhu 241000, Anhui Province, China.
World J Psychiatry. 2025 Jul 19;15(7):107038. doi: 10.5498/wjp.v15.i7.107038.
Recent studies have revealed that patients with septic shock and acute skin failure (ASF) exhibit significantly higher levels of inflammatory cytokines, lactate, and C-reactive protein, along with elevated skin mottling score; modified early warning score (MEWS); and anxiety, depression, and Pittsburgh sleep quality index scores compared to those without ASF. Notably, these indicators are significantly correlated. Patients with septic shock accompanied by ASF tend to have a mean MEWS greater than 9, indicating severe disease progression. Therefore, it is essential to not only manage septic shock but also mitigate anxiety, depression, sleep disorders, and disturbances of consciousness. This article explores the impact of severe anxiety, depression, and sleep disorders on the prognosis of septic shock and discusses intervention strategies.
最近的研究表明，与没有急性皮肤衰竭（ASF）的患者相比，感染性休克和急性皮肤衰竭患者的炎症细胞因子、乳酸和C反应蛋白水平显著更高，同时皮肤花斑评分、改良早期预警评分（MEWS）以及焦虑、抑郁和匹兹堡睡眠质量指数评分也有所升高。值得注意的是，这些指标显著相关。伴有ASF的感染性休克患者的平均MEWS往往大于9，表明疾病进展严重。因此，不仅要治疗感染性休克，还必须减轻焦虑、抑郁、睡眠障碍和意识障碍。本文探讨了严重焦虑、抑郁和睡眠障碍对感染性休克预后的影响，并讨论了干预策略。
