Department of Neurology and Neuro-Rehabilitation, Herz-Kreislauf-Zentrum, Klinikum Hersfeld-Rotenburg GmbH, Rotenburg a. F., University of Leipzig, Leipzig, Germany.
Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Crit Care. 2023 Jul 31;27(1):301. doi: 10.1186/s13054-023-04569-5.
Intensive Care Unit (ICU) survivors often experience several impairments in their physical, cognitive, and psychological health status, which are labeled as post-intensive care syndrome (PICS). The aim of this work is to develop a multidisciplinary and -professional guideline for the rehabilitative therapy of PICS.
A multidisciplinary/-professional task force of 15 healthcare professionals applied a structured, evidence-based approach to address 10 scientific questions. For each PICO-question (Population, Intervention, Comparison, and Outcome), best available evidence was identified. Recommendations were rated as "strong recommendation", "recommendation" or "therapy option", based on Grading of Recommendations, Assessment, Development and Evaluation principles. In addition, evidence gaps were identified.
The evidence resulted in 12 recommendations, 4 therapy options, and one statement for the prevention or treatment of PICS.
early mobilization, motor training, and nutrition/dysphagia management should be performed. Delirium prophylaxis focuses on behavioral interventions. ICU diaries can prevent/treat psychological health issues like anxiety and post-traumatic stress disorders. Early rehabilitation approaches as well as long-term access to specialized rehabilitation centers are recommended. Therapy options include additional physical rehabilitation interventions. Statement: A prerequisite for the treatment of PICS are the regular and repeated assessments of the physical, cognitive and psychological health in patients at risk for or having PICS.
PICS is a variable and complex syndrome that requires an individual multidisciplinary, and multiprofessional approach. Rehabilitation of PICS should include an assessment and therapy of motor-, cognitive-, and psychological health impairments.
重症监护病房(ICU)幸存者通常会在身体、认知和心理健康方面出现多种损伤,这些损伤被称为重症监护后综合征(PICS)。本研究旨在制定针对 PICS 康复治疗的多学科和多专业指南。
由 15 名医疗保健专业人员组成的多学科/多专业工作组采用结构化、循证方法解决了 10 个科学问题。对于每个 PICO 问题(人群、干预、比较和结局),都确定了最佳可用证据。根据推荐分级评估、制定与评价(GRADE)原则,推荐意见被评为“强烈推荐”、“推荐”或“治疗选择”。此外,还确定了证据差距。
证据产生了 12 项推荐意见、4 种治疗选择和 1 项预防或治疗 PICS 的陈述。
应进行早期动员、运动训练和营养/吞咽困难管理。预防谵妄的重点是行为干预。重症监护病房日记可预防/治疗焦虑和创伤后应激障碍等心理健康问题。建议早期康复方法以及长期获得专门的康复中心。治疗选择包括额外的物理康复干预。陈述:治疗 PICS 的前提是定期和反复评估有或易发生 PICS 的患者的身体、认知和心理健康状况。
PICS 是一种多变且复杂的综合征,需要采用个体化的多学科和多专业方法。PICS 的康复治疗应包括对运动、认知和心理健康损伤的评估和治疗。