Maggiore G, de Giacomo C, Marzani M D, Colombo A, Scotta M S
Arch Fr Pediatr. 1985 Oct;42(8):683-5.
In order to evaluate the intrafamilial spread of hepatitis B virus (HBV) infection we studied the serological markers of HBV in 101 relatives of 35 children with chronic hepatitis B. Sixty per cent of relatives had markers of infection and 25% showed persistent HBs antigenemia. The high prevalence of HBeAg versus anti-HBe in chronically infected relatives suggests a close temporal relationship of the infection between adults and children. These results support the hypothesis that the child is the main carrier of HBV infection in his family.
为了评估乙型肝炎病毒（HBV）感染在家族内的传播情况，我们研究了35名慢性乙型肝炎患儿的101名亲属的HBV血清学标志物。60%的亲属有感染标志物，25%表现为持续性HBs抗原血症。慢性感染亲属中HBeAg与抗-HBe的高流行率表明成人和儿童之间的感染存在密切的时间关系。这些结果支持了儿童是其家庭中HBV感染主要携带者这一假说。
