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咬伤与心脏并发症:一例病例报告及文献综述

bite and cardiac complications: A case report and review of literature.

作者信息

Acosta Juan S, Cifuentes Tarquino Jennifer, Arteaga Joshua E

机构信息

Department of Cardiology, Medicadiz, Ibague 730001, Tolima, Colombia.

出版信息

World J Cardiol. 2025 Jul 26;17(7):106828. doi: 10.4330/wjc.v17.i7.106828.

Abstract

BACKGROUND

envenomation is a common medical emergency in tropical areas and is characterized by local and systemic complications, such as edema, coagulopathy, and tissue necrosis. Cardiovascular manifestations are rare and poorly documented, contributing to the complexity of its clinical management.

CASE SUMMARY

We described a rare cardiac complication in a 65-year-old female patient, who initially presented with mild envenomation. She experienced localized edema and erythema but with a lack of systemic symptoms. During the evaluation we detected asymptomatic sinus bradycardia and QTc prolongation (523 milliseconds) that progressed to severe arrhythmias that required implantation of a permanent pacemaker. Management included the administration of polyvalent antiphonic serum, fresh frozen plasma transfusions, and intensive care unit monitoring. Imaging and laboratory studies ruled out ischemic, metabolic, or electrolytic etiologies for the cardiac alterations. The patient recovered favorably after the intervention and was discharged without further complications.

CONCLUSION

This case underscored the need for cardiac monitoring after snakebite envenomation as well as further research on venom-induced cardiotoxic mechanisms.

摘要

背景

中毒是热带地区常见的医疗急症,其特征为局部和全身并发症,如水肿、凝血病和组织坏死。心血管表现罕见且记录不足,这增加了其临床管理的复杂性。

病例摘要

我们描述了一名65岁女性患者罕见的心脏并发症,该患者最初表现为轻度中毒。她出现局部水肿和红斑,但无全身症状。在评估过程中,我们检测到无症状性窦性心动过缓和QTc延长(523毫秒),随后进展为严重心律失常,需要植入永久性起搏器。治疗措施包括给予多价抗蛇毒血清、输注新鲜冷冻血浆以及在重症监护病房进行监测。影像学和实验室检查排除了心脏改变的缺血、代谢或电解质病因。患者在干预后恢复良好,出院时无进一步并发症。

结论

该病例强调了蛇咬伤中毒后进行心脏监测的必要性,以及对毒液诱导的心脏毒性机制进行进一步研究的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15e/12304819/61fd63af76ee/wjc-17-7-106828-g001.jpg

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