• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一种由源自百里香叶或地上部分的酊剂组成的饲料添加剂(野生百里香酊剂)用于所有动物物种的安全性和有效性(FEFANA asbl) 。

Safety and efficacy of a feed additive consisting of a tincture derived from the leaves or aerial parts of L. (wild thyme tincture) for use in all animal species (FEFANA asbl).

作者信息

Villa Roberto Edoardo, Azimonti Giovanna, Bonos Eleftherios, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Gehring Ronette, Glandorf Boet, Kouba Maryline, López-Alonso Marta, Marcon Francesca, Nebbia Carlo, Pechová Alena, Prieto-Maradona Miguel, Röhe Ilen, Theodoridou Katerina, Bastos Maria de Lourdes, Benfenati Emilio, Brantom Paul, Chesson Andrew, Schlatter Josef, Westendorf Johannes, Manini Paola

出版信息

EFSA J. 2025 Jul 30;23(7):e9551. doi: 10.2903/j.efsa.2025.9551. eCollection 2025 Jul.

DOI:10.2903/j.efsa.2025.9551
PMID:40741370
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12308907/
Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a tincture from the leaves or aerial parts of L. (wild thyme tincture) when used as a sensory additive in feed and in water for drinking for all animal species. The product is a ■■■■■ solution, with a dry matter content of approximately 1.0%. The product contains on average 0.083% (w/w) total polyphenols (of which 0.0222% are flavonoids). The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the use of wild thyme tincture is safe at the proposed use level of 500 mg/kg complete feed for ornamental fish. For the other species the calculated safe concentrations in complete feed are: 71 mg/kg for chickens for fattening, 106 mg/kg for laying hens, 96 mg/kg for turkeys for fattening, 154 mg/kg for pigs for fattening, 128 mg/kg for piglets, 187 mg/kg for sows, 321 mg/kg for veal calves, 282 mg/kg for cattle for fattening, sheep/goats and horses, 183 mg/kg for dairy cows, 113 mg/kg for rabbits, 322 mg/kg for salmonids, 338 mg/kg for dogs and 282 mg/kg for cats. These conclusions were extrapolated to other physiologically related species. For any other species, the additive is safe at 71 mg/kg complete feed. No safety concerns were identified for the consumer and the environment from the use of the additive in animal feed. Regarding user safety, the additive under assessment should be considered as irritant to skin and eyes, and as a dermal and respiratory sensitiser. Any exposure is considered a risk. Since the leaves of are recognised to flavour food and their function in feed would be essentially the same as that in food, no further demonstration of efficacy was necessary.

摘要

应欧盟委员会要求,欧洲食品安全局(EFSA)被要求就L.叶或地上部分的酊剂(野生百里香酊剂)在所有动物物种的饲料和饮用水中用作感官添加剂时的安全性和有效性发表科学意见。该产品为一种■■■■■溶液,干物质含量约为1.0%。该产品平均含有0.083%(w/w)的总多酚(其中0.0222%为黄酮类化合物)。动物饲料添加剂和产品或物质专家小组(FEEDAP)得出结论,在观赏鱼全价饲料中按建议使用水平500 mg/kg使用野生百里香酊剂是安全的。对于其他物种,全价饲料中计算出的安全浓度为:育肥鸡71 mg/kg,产蛋鸡106 mg/kg,育肥火鸡96 mg/kg,育肥猪154 mg/kg,仔猪128 mg/kg,母猪187 mg/kg,犊牛321 mg/kg,育肥牛、绵羊/山羊和马282 mg/kg,奶牛183 mg/kg,兔子113 mg/kg,鲑鱼322 mg/kg,狗338 mg/kg,猫282 mg/kg。这些结论已外推至其他生理相关物种。对于任何其他物种,该添加剂在全价饲料中71 mg/kg时是安全的。在动物饲料中使用该添加剂对消费者和环境未发现安全问题。关于使用者安全,所评估的添加剂应被视为对皮肤和眼睛有刺激性,以及皮肤和呼吸道致敏剂。任何接触都被视为有风险。由于L.的叶子被认为可用于调味食品,其在饲料中的功能与在食品中的基本相同,因此无需进一步证明其有效性。

相似文献

1
Safety and efficacy of a feed additive consisting of a tincture derived from the leaves or aerial parts of L. (wild thyme tincture) for use in all animal species (FEFANA asbl).一种由源自百里香叶或地上部分的酊剂组成的饲料添加剂(野生百里香酊剂)用于所有动物物种的安全性和有效性(FEFANA asbl) 。
EFSA J. 2025 Jul 30;23(7):e9551. doi: 10.2903/j.efsa.2025.9551. eCollection 2025 Jul.
2
Safety and efficacy of a feed additive consisting of a tincture derived from the leaves or the aerial parts of  ×  L. (peppermint tincture) for use in all animal species (FEFANA asbl).一种由源自薄荷(×L.)叶子或地上部分的酊剂组成的饲料添加剂用于所有动物物种的安全性和有效性(欧洲动物营养添加剂和预混料协会)
EFSA J. 2025 Jul 30;23(7):e9544. doi: 10.2903/j.efsa.2025.9544. eCollection 2025 Jul.
3
Safety and efficacy of a feed additive consisting of a tincture derived from the leaves of L. (sage tincture) for use in all animal species (FEFANA asbl).一种由鼠尾草叶提取物酊剂组成的饲料添加剂用于所有动物物种的安全性和有效性(欧洲动物营养添加剂和预混料协会)
EFSA J. 2025 Jul 30;23(7):e9545. doi: 10.2903/j.efsa.2025.9545. eCollection 2025 Jul.
4
Safety and efficacy of a feed additive consisting of a tincture derived from the leaves of L. (basil tincture) for use in all animal species (FEFANA asbl).一种由罗勒叶酊剂组成的饲料添加剂用于所有动物物种的安全性和有效性(FEFANA asbl)。
EFSA J. 2025 Jul 30;23(7):e9543. doi: 10.2903/j.efsa.2025.9543. eCollection 2025 Jul.
5
Safety and efficacy of a feed additive consisting of a tincture derived from the flowers of Mill. (lavender tincture) for use in all animal species (FEFANA asbl).一种由取自Mill.花的酊剂(薰衣草酊剂)组成的饲料添加剂用于所有动物物种的安全性和有效性(欧洲动物营养添加剂和预混料协会)
EFSA J. 2025 Jul 30;23(7):e9550. doi: 10.2903/j.efsa.2025.9550. eCollection 2025 Jul.
6
Assessment of the feed additive consisting of 6-phytase (produced with CBS 126897) (Quantum® Blue) for the renewal of its authorisation for poultry, weaned piglets, pigs for fattening and sows (4a19), and its extension of use to other porcine species and ornamental birds (AB Enzymes Finland Oy).评估由6-植酸酶(由CBS 126897生产)(Quantum® Blue)组成的饲料添加剂,以更新其在家禽、断奶仔猪、育肥猪和母猪(4a19)方面的授权,并将其使用范围扩大到其他猪种和观赏鸟(芬兰AB酶公司)。
EFSA J. 2025 Jun 18;23(6):e9463. doi: 10.2903/j.efsa.2025.9463. eCollection 2025 Jun.
7
Safety and efficacy of a feed additive consisting of CECT 5940 (Ecobiol®) for laying hens and other birds for egg production (Evonik Operations GmbH).由CECT 5940(益生素®)组成的饲料添加剂对蛋鸡及其他产蛋禽类的安全性和有效性(赢创工业运营有限公司)
EFSA J. 2025 Jul 24;23(7):e9554. doi: 10.2903/j.efsa.2025.9554. eCollection 2025 Jul.
8
Safety of the preparation of monensin sodium (Coxidin®) produced with sp. LMG S-19095 as a coccidiostat for chickens for fattening and chickens reared for laying (Huvepharma N.V.).以LMG S - 19095菌株生产的莫能菌素钠(Coxidin®)作为育肥鸡和产蛋鸡抗球虫药的安全性(Huvepharma N.V.)
EFSA J. 2025 Jul 24;23(7):e9541. doi: 10.2903/j.efsa.2025.9541. eCollection 2025 Jul.
9
Safety and efficacy of a feed additive consisting of 4-hydroxy-2,5-dimethylfuran-3(2H)-one for all animal species other than dogs and cats (ADISSEO France SAS, ADM International Sàrl, Laboratoires Phodé S.A.S., LUCTA S.A., Norel, S.A.).一种由4-羟基-2,5-二甲基呋喃-3(2H)-酮组成的饲料添加剂对犬猫以外所有动物物种的安全性和有效性(法国安迪苏公司、ADM国际公司、Phodé实验室公司、卢克塔公司、诺雷尔公司)
EFSA J. 2025 Jul 16;23(7):e9538. doi: 10.2903/j.efsa.2025.9538. eCollection 2025 Jul.
10
Assessment of the feed additive consisting of endo-1,3(4)-beta-glucanase and endo-1,4-beta-xylanase (ROVABIO® ADVANCE) for chickens for fattening and reared for laying, laying hens, turkeys for fattening and reared for breeding, and minor poultry species for fattening and reared for laying for the renewal of its authorisation and for its extension of use to all poultry species (Adisseo France SAS).评估由内切-1,3(4)-β-葡聚糖酶和内切-1,4-β-木聚糖酶组成的饲料添加剂(ROVABIO® ADVANCE)对育肥鸡、蛋鸡、产蛋母鸡、育肥火鸡、种用火鸡以及育肥和产蛋小型家禽的适用性,以更新其授权并将其使用范围扩展至所有家禽品种(安迪苏法国有限公司)。
EFSA J. 2025 Jul 23;23(7):e9547. doi: 10.2903/j.efsa.2025.9547. eCollection 2025 Jul.

本文引用的文献

1
Safety and efficacy of secondary alicyclic saturated and unsaturated alcohols, ketones, ketals and esters with ketals containing alicyclic alcohols or ketones and esters containing secondary alicyclic alcohols from chemical group 8 when used as flavourings for all animal species.化学组8中含脂环族醇或酮的缩酮以及含仲脂环族醇的酯的仲脂环族饱和与不饱和醇、酮、缩酮和酯用作所有动物物种的调味剂时的安全性和有效性。
EFSA J. 2016 Jun 3;14(6):e04475. doi: 10.2903/j.efsa.2016.4475. eCollection 2016 Jun.
2
Safety and efficacy of α,β-unsaturated straight-chain and branched-chain aliphatic primary alcohols, aldehydes, acids and esters belonging to chemical group 3 when used as flavourings for all animal species.化学组3中的α,β-不饱和直链和支链脂肪族伯醇、醛、酸和酯用作所有动物物种的调味剂时的安全性和有效性。
EFSA J. 2016 Jun 24;14(6):e04512. doi: 10.2903/j.efsa.2016.4512. eCollection 2016 Jun.
3
Guidance on the assessment of the efficacy of feed additives.饲料添加剂功效评估指南。
EFSA J. 2024 Jul 17;22(7):e8856. doi: 10.2903/j.efsa.2024.8856. eCollection 2024 Jul.
4
Guidance on the assessment of the safety of feed additives for the users.饲料添加剂使用者安全评估指南。
EFSA J. 2023 Dec 6;21(12):e8469. doi: 10.2903/j.efsa.2023.8469. eCollection 2023 Dec.
5
Safety of 41 flavouring compounds providing a herbal flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl).41种具有草药风味且属于不同化学类别的调味化合物用作所有动物种类饲料添加剂的安全性(FEFANA asbl)
EFSA J. 2023 Oct 25;21(10):e08340. doi: 10.2903/j.efsa.2023.8340. eCollection 2023 Oct.
6
Camphor in flavourings and other food ingredients with flavouring properties - Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food on a request from the Commission.调味剂及其他具有调味特性的食品配料中的樟脑——食品添加剂、调味剂、加工助剂及与食品接触材料科学小组应委员会要求给出的意见
EFSA J. 2008 Jul 30;6(7):729. doi: 10.2903/j.efsa.2008.729. eCollection 2008 Jul.
7
Safety and efficacy of a feed additive consisting of an essential oil from the leaves of (P.J. Bergius) Pillans (buchu leaf oil) for use in all animal species (FEFANA asbl).一种由(P.J. 贝吉乌斯)皮兰斯(布枯叶油)叶中的精油组成的饲料添加剂用于所有动物物种的安全性和有效性(欧洲动物营养添加剂和预混料协会)
EFSA J. 2022 Mar 8;20(3):e07160. doi: 10.2903/j.efsa.2022.7160. eCollection 2022 Mar.
8
Safety and efficacy of feed additives consisting of expressed lemon oil and its fractions from (L.) Osbeck and of lime oil from (Christm.) Swingle for use in all animal species (FEFANA asbl).由柠檬(Citrus limon (L.) Osbeck)压榨的柠檬油及其馏分和酸橙(Citrus aurantifolia (Christm.) Swingle)压榨的酸橙油组成的饲料添加剂在所有动物种类中的安全性和有效性(欧洲动物营养添加剂和预混料协会)
EFSA J. 2021 Apr 30;19(4):e06548. doi: 10.2903/j.efsa.2021.6548. eCollection 2021 Apr.
9
Guidance on the use of the Threshold of Toxicological Concern approach in food safety assessment.食品安全评估中毒理学关注阈值方法的使用指南。
EFSA J. 2019 Jun 6;17(6):e05708. doi: 10.2903/j.efsa.2019.5708. eCollection 2019 Jun.
10
Guidance on the assessment of the safety of feed additives for the environment.饲料添加剂对环境安全性的评估指南。
EFSA J. 2019 Apr 5;17(4):e05648. doi: 10.2903/j.efsa.2019.5648. eCollection 2019 Apr.