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由柠檬(Citrus limon (L.) Osbeck)压榨的柠檬油及其馏分和酸橙(Citrus aurantifolia (Christm.) Swingle)压榨的酸橙油组成的饲料添加剂在所有动物种类中的安全性和有效性(欧洲动物营养添加剂和预混料协会)

Safety and efficacy of feed additives consisting of expressed lemon oil and its fractions from (L.) Osbeck and of lime oil from (Christm.) Swingle for use in all animal species (FEFANA asbl).

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Kouba Maryline, Fašmon Durjava Mojca, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Brantom Paul, Chesson Andrew, Westendorf Johannes, Galobart Jaume, Manini Paola, Pizzo Fabiola, Dusemund Birgit

出版信息

EFSA J. 2021 Apr 30;19(4):e06548. doi: 10.2903/j.efsa.2021.6548. eCollection 2021 Apr.

Abstract

Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of expressed lemon oil and distilled lemon oil from (L.) Osbeck and lime oil from (Christm.) Swingle, when used as sensory additives in feed for all animal species. The use of the expressed lemon oil and its residual fraction and the use of lime oil in feed is not expected to increase the exposure to furocoumarins and methoxycoumarins and perillaldehyde of those target species that are already fed citrus by-products a relevant extent (< 10%). For companion animals and ornamental fish not normally exposed to citrus by-products, no conclusion can be drawn. For the other species and for the distilled fraction of expressed lemon oil, the FEEDAP Panel concludes that the additives under assessment are safe at the maximum proposed or at reduced use levels in complete feed. The Panel considers that the use in water for drinking is safe provided that the total daily intake of the additive does not exceed the daily amount that is considered safe when consumed via feed. No concerns for consumer safety were identified following the use of the additives at the maximum proposed use level in feed. The additives under assessment should be considered as irritants to skin and eyes and the respiratory tract and as skin sensitisers. Since expressed lemon oil and its fractions contain furocoumarins, they may cause phototoxicity. The use of the additives under the proposed conditions of use in animal feed is not expected to pose a risk for the environment. Since and their preparations are recognised to flavour food and its function in feed would be essentially the same as that in food, no further demonstration of efficacy is considered necessary.

摘要

应欧盟委员会的要求,欧洲食品安全局动物饲料添加剂和产品或物质专家小组(FEEDAP)被要求就甜橙(Citrus sinensis (L.) Osbeck)压榨柠檬油、蒸馏柠檬油以及酸橙(Citrus aurantifolia (Christm.) Swingle)油作为所有动物饲料感官添加剂的安全性和有效性发表科学意见。预计在饲料中使用压榨柠檬油及其残留部分以及酸橙油,不会使已摄入相关程度柑橘副产品(<10%)的目标物种对香豆素、甲氧基香豆素和紫苏醛的暴露量增加。对于通常不接触柑橘副产品的伴侣动物和观赏鱼,无法得出结论。对于其他物种以及压榨柠檬油的蒸馏部分,FEEDAP专家小组得出结论,在所提议的最高使用水平或降低的使用水平下,评估中的添加剂在全价饲料中是安全的。专家小组认为,若添加剂的每日总摄入量不超过通过饲料摄入时被认为安全的每日量,则用于饮用水是安全的。在饲料中按提议的最高使用水平使用添加剂后,未发现对消费者安全的担忧。评估中的添加剂应被视为对皮肤、眼睛和呼吸道有刺激性且为皮肤致敏剂。由于压榨柠檬油及其馏分含有香豆素,它们可能会引起光毒性。在所提议的动物饲料使用条件下使用这些添加剂预计不会对环境构成风险。由于甜橙和酸橙及其制剂被认为可用于食品调味,其在饲料中的功能与在食品中的功能基本相同,因此无需进一步证明其有效性。

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