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Effects of neuromuscular block reversal with neostigmine/glycopyrrolate versus sugammadex on bowel motility recovery after laparoscopic colorectal surgery: A randomized controlled trial.新斯的明/格隆溴铵与琥珀胆碱逆转肌松作用对腹腔镜结直肠手术后肠动力恢复的影响:一项随机对照试验。
J Clin Anesth. 2024 Nov;98:111588. doi: 10.1016/j.jclinane.2024.111588. Epub 2024 Aug 21.
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Impact of Performance Status on Survival Outcomes and Health Care Utilization in Patients With Advanced NSCLC Treated With Immune Checkpoint Inhibitors.体能状态对接受免疫检查点抑制剂治疗的晚期非小细胞肺癌患者生存结局和医疗保健利用的影响。
JTO Clin Res Rep. 2023 Feb 24;4(4):100482. doi: 10.1016/j.jtocrr.2023.100482. eCollection 2023 Apr.
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Effect of early physical therapy interventions on post-operative ileus following abdominal hysterectomy.早期物理治疗干预对腹部子宫切除术后肠麻痹的影响。
J Pak Med Assoc. 2023 Mar;73(3):650-652. doi: 10.47391/JPMA.5447.
4
Prevention and Management of Postoperative Ileus: A Review of Current Practice.术后肠梗阻的预防与管理:当前实践综述
Cureus. 2022 Feb 27;14(2):e22652. doi: 10.7759/cureus.22652. eCollection 2022 Feb.
5
Postoperative ileus: A pharmacological perspective.术后肠梗阻:药理学视角。
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Post-operative ileus: definitions, mechanisms and controversies.术后肠麻痹:定义、机制和争议。
ANZ J Surg. 2022 Jan;92(1-2):62-68. doi: 10.1111/ans.17297. Epub 2021 Oct 22.
8
Reducing ileus after colorectal surgery: A network meta-analysis of therapeutic interventions.减少结直肠手术后的肠梗阻:治疗干预的网络荟萃分析。
Clin Nutr. 2021 Jul;40(7):4772-4782. doi: 10.1016/j.clnu.2021.05.030. Epub 2021 Jun 5.
9
Incidence and Risk of Severe Ileus After Orthopedic Surgery: A Case-Control Study.骨科手术后严重肠梗阻的发病率及风险:一项病例对照研究
HSS J. 2020 Dec;16(Suppl 2):272-279. doi: 10.1007/s11420-019-09712-z. Epub 2019 Aug 16.
10
Clinical Importance, Incidence and Risk Factors for the Development of Postoperative Ileus Following Adult Spinal Deformity Surgery.成人脊柱畸形手术后肠梗阻发生的临床重要性、发病率及危险因素
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埃塞俄比亚非腹部手术后肠梗阻的发病率及临床预测因素:一项前瞻性队列研究。

Incidence and clinical predictors of postoperative ileus following non-abdominal surgery in Ethiopia: a prospective cohort study.

作者信息

Wubet Habtie Bantider, Gobezie Negesse Zurbachew, Asmare Temesgen Birlie, Diress Getachew Mekete, Alachew Moges Kefale, Mossie Kaletsidk Desalegn, Mekuriaw Begizew Yimenu, Mebratie Alemie Fentie, Setargew Kidist Hunegn, Teshome Diriba

机构信息

Department of Anesthesia, School of Medicine, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.

Department of Midwifery, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.

出版信息

Langenbecks Arch Surg. 2025 Jul 31;410(1):236. doi: 10.1007/s00423-025-03808-3.

DOI:10.1007/s00423-025-03808-3
PMID:40742541
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12313793/
Abstract

BACKGROUND

Postoperative ileus (POI) is a common consequence following abdominal surgeries; however, its incidence and risk factors in non-abdominal procedures remain unknown. Identifying clinical indicators of POI in this population is essential for early detection and treatment.

OBJECTIVE

This study aims to assess the incidence and determinants of postoperative ileus (POI) in patients undergoing non-abdominal surgeries at Debre Tabor Comprehensive Specialized Hospital.

METHODS

A prospective cohort study was conducted between September 1, 2024, and January 30, 2025. Demographic characteristics, comorbidities, surgical details, and perioperative parameters were recorded. Data were analyzed using SPSS version 27, with continuous and categorical variables summarized using descriptive statistics. Independent predictors of postoperative ileus (POI) were identified through bivariate and multivariate logistic regression analyses.

RESULTS

Among the 400 patients who underwent elective non-abdominal surgery, 31 (7.75%) developed postoperative ileus (POI). Significant predictors included opioid use (OR = 3.28 [95% CI, 2.25-7.12], P < 0.01), neuromuscular blockers (OR = 2.33 [95% CI, 2.01-5.12], P < 0.01), poor postoperative functional status (OR = 5.67 [95% CI, 3.41-8.91], P < 0.01), and delayed postoperative mobility (OR = 4.45 [95% CI, 2.05-8.17], P < 0.01).

RECOMMENDATION AND CONCLUSION

POI occurs in a significant proportion of patients undergoing non-abdominal surgery. Implementing targeted perioperative strategies may reduce the incidence of POI and enhance postoperative outcomes.

摘要

背景

术后肠梗阻(POI)是腹部手术后常见的后果;然而,其在非腹部手术中的发生率和危险因素尚不清楚。确定该人群中POI的临床指标对于早期发现和治疗至关重要。

目的

本研究旨在评估德布雷塔博尔综合专科医院接受非腹部手术患者术后肠梗阻(POI)的发生率及其决定因素。

方法

于2024年9月1日至2025年1月30日进行了一项前瞻性队列研究。记录了人口统计学特征、合并症、手术细节和围手术期参数。使用SPSS 27版进行数据分析,连续变量和分类变量采用描述性统计进行汇总。通过二元和多因素逻辑回归分析确定术后肠梗阻(POI)的独立预测因素。

结果

在400例接受择期非腹部手术的患者中,31例(7.75%)发生了术后肠梗阻(POI)。显著的预测因素包括使用阿片类药物(OR = 3.28 [95% CI,2.25 - 7.12],P < 0.01)、神经肌肉阻滞剂(OR = 2.33 [95% CI,2.01 - 5.