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头部和身体约束对松鼠猴实验性运动病的影响。

Effects of head and body restraint on experimental motion-induced sickness in squirrel monkeys.

作者信息

Wilpizeski C R, Lowry L D, Contrucci R B, Green S J, Goldman W S

出版信息

Aviat Space Environ Med. 1985 Nov;56(11):1070-3.

PMID:4074259
Abstract

Each of 16 Bolivian-phenotype squirrel monkeys of mixed sex had a machine bolt mounted on the skull with acrylic cement; 13 were provided with temporary plaster body casts allowing free movement. With eyes open, all were rotated in the horizontal plane at 30 rpm every other day until vomiting occurred or for a maximum duration of 120 min/spin. Latencies for motion-sickness signs were recorded under three experimental conditions: free movement, torso fixed to an aluminum frame and both torso and head restrained by bolting to the frame. Subsequently, 10 monkeys from this sample were rotated while blindfolded with head and torso immobilized. Results partially confirmed human and animal findings reported by others: reduced mobility was accompanied by a reduction in the incidence and an increase in the latency of motion sickness. The importance of optokinetic input for the generation of motion sickness in this species was clear.

摘要

16只混合性别的玻利维亚表型松鼠猴,每只都用丙烯酸水泥将一个机器螺栓安装在头骨上;13只猴子被制作了临时石膏身体模型以允许自由活动。猴子们睁开眼睛,每隔一天在水平面以30转/分钟的速度旋转,直到出现呕吐或每次旋转最长持续120分钟。在三种实验条件下记录晕动病症状的潜伏期:自由活动、躯干固定在铝制框架上以及躯干和头部都通过螺栓固定在框架上。随后,从这个样本中选取10只猴子,在蒙眼且头部和躯干固定不动的情况下进行旋转。结果部分证实了其他人报告的人类和动物研究结果:活动能力降低伴随着晕动病发病率的降低和潜伏期的延长。视动输入对该物种晕动病产生的重要性是显而易见的。

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