Wilpizeski C R, Lowry L D, Miller R
Otolaryngol Head Neck Surg. 1986 Jun;94(5):628-32. doi: 10.1177/019459988609400517.
The aim of this research was to quantify the development of habituation or intensification of experimental motion sickness induced in Bolivian squirrel monkeys by repeated exposures to horizontal rotation. Incidence, frequency, and latency of vomiting responses were recorded from monkeys rotated daily in a transparent testing chamber at 30 rpm for periods of 1 or 2 hours. Data showed that more than half of the subjects revealed habituation in terms of increased latencies for vomiting. Some showed a tendency to vomit increasingly earlier with multiple daily exposures to rotation. The development of habituation and intensification was evident as early as the second day of rotation. The number of emetic episodes per day decreased as a consequence of repeated rotation, but intensification of vomiting frequency did not occur beyond the fifth day.
本研究的目的是量化玻利维亚松鼠猴因反复暴露于水平旋转而诱发的实验性晕动病的习惯化或强化发展情况。记录每天在透明测试室中以30转/分钟的速度旋转1或2小时的猴子呕吐反应的发生率、频率和潜伏期。数据显示，超过一半的受试者在呕吐潜伏期延长方面表现出习惯化。一些猴子在每天多次暴露于旋转时，呕吐倾向越来越早出现。习惯化和强化发展早在旋转的第二天就很明显。由于反复旋转，每天呕吐发作的次数减少，但呕吐频率的强化在第五天之后并未发生。
