Caldecourt M A, Cox D J, Sugden M C, Palmer T N
Biochem J. 1985 Nov 1;231(3):801-4. doi: 10.1042/bj2310801.
In quarter-diaphragms from 40 h-starved rats the rate of glycogen mobilization is sufficient to account for the rate of lactate+pyruvate+alanine production. It is concluded, therefore, that alanine derives its carbon skeleton predominantly via glycolysis and not via synthesis de novo from tricarboxylic acid-cycle intermediates and related amino acids.
在40小时饥饿大鼠的四分之一膈肌中,糖原动员速率足以解释乳酸+丙酮酸+丙氨酸的产生速率。因此可以得出结论,丙氨酸的碳骨架主要通过糖酵解获得,而非由三羧酸循环中间体和相关氨基酸从头合成。