Goldstein L, Newsholme E A
Biochem J. 1976 Feb 15;154(2):555-8. doi: 10.1042/bj1540555.
Alanine production and pyruvate content of the isolated rat hemidiaphragm are increased by isoleucine or glutamate. These results support the hypothesis that amino acids are converted into pyruvate before oxidation and that some pyruvate is transaminated to alanine, which is released from the muscle.
异亮氨酸或谷氨酸可增加离体大鼠半膈肌的丙氨酸生成量和丙酮酸含量。这些结果支持以下假说:氨基酸在氧化之前先转化为丙酮酸,并且一些丙酮酸经转氨作用生成丙氨酸,丙氨酸从肌肉中释放出来。