Liu Yanan, Cheng Yanwei, Sun Xiaofei, Chen Cancan, Yang Shuhua, Wang Dong Yang, Ren Ying
Department of ICU, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
School of Humanities and Design, Zhengzhou Vocational University of Information and Technology, Zhengzhou, Henan, China.
Sci Rep. 2025 Jul 31;15(1):20001. doi: 10.1038/s41598-025-01416-1.
Multidrug-resistant organism (MDRO) infections pose significant challenges in intensive care settings. This prospective study aimed to evaluate the impact of a Specific, Measurable, Achievable, Relevant, and Time-bound (SMART) infection control plan on MDRO prevention among healthcare workers in an emergency intensive care unit (ICU). Fifty healthcare workers participated, and pre- and post-intervention assessments were conducted to measure changes in MDRO prevention indicators. Following implementation of the SMART-based plan, there was a statistically significant improvement in staff knowledge (p < 0.05), with increased hand hygiene compliance (72.1-94.2%) and isolation gown use (60.2-87.6%). MDRO infection rates decreased from 8.0 to 5.1% post-intervention (p = 0.027). These findings demonstrate the effectiveness of the SMART-based infection control plan in reducing MDRO infection rates and improving staff compliance in the emergency ICU setting.
多重耐药菌（MDRO）感染在重症监护环境中构成了重大挑战。这项前瞻性研究旨在评估一项具体、可衡量、可实现、相关且有时限（SMART）的感染控制计划对急诊重症监护病房（ICU）医护人员预防MDRO的影响。50名医护人员参与其中，并在干预前后进行评估，以衡量MDRO预防指标的变化。实施基于SMART的计划后，工作人员的知识水平有统计学意义的提高（p<0.05），手卫生依从性增加（从72.1%提高到94.2%），隔离衣使用率增加（从60.2%提高到87.6%）。干预后MDRO感染率从8.0%降至5.1%（p=0.027）。这些发现表明，基于SMART的感染控制计划在降低急诊ICU环境中MDRO感染率和提高工作人员依从性方面是有效的。
