Moeini-Naghani Iman, Syed Shoaib A, Jain Ankita, Spirollari Eris, Sacknovitz Ariel, Frid Ilya, Elmashad Ahmed, Kaur Gurmeen, Gandhi Chirag D, Al-Mufti Fawaz
Department of Neurology, Westchester Medical Center, Valhalla, NY, USA.
Department of Neurosurgery, Westchester Medical Center, Valhalla, NY, USA.
Interv Neuroradiol. 2025 Aug 1:15910199251350216. doi: 10.1177/15910199251350216.
PurposeEndovascular treatment has become the standard of care for the treatment of patients with acute ischemic stroke with large vessel occlusion, however, the optimal first-line strategy for mechanical thrombectomy continues to be debated. Recent advancements in large-bore aspiration catheters have enhanced the efficacy of A Direct Aspiration First Pass Technique (ADAPT), offering promising improvements in procedural success. This study aims to evaluate the characteristics and technical outcomes associated with endovascular treatment for acute ischemic stroke following the inaugural global use of the CEREGLIDE™ 71 Intermediate Catheter at our institution.Materials and methodsIn this retrospective, single-center study, a total of 25 consecutive patients with verified large vessel occlusion in the anterior circulation were included from October 2023 to May 2024. All patients were treated with endovascular therapy using a CEREGLIDE™ 71 intermediate catheter. The angiographic outcome was assessed using the thrombolysis in cerebral infarction (TICI) scale.ResultsA total of 25 patients were included in the study. The mean age at baseline was 72.3 years old, and 52% of patients were female. Mean National Institutes of Health Stroke Scale score at admission was 16.4. Occlusion locations included the M1 segment of the middle cerebral artery (MCA) (60%), internal carotid artery terminus (20%), and M2 segment of MCA (16%). The average number of passes per intervention was 2.2. Successful reperfusion (TICI 2b, TICI 2c, and TICI 3) was achieved in 88% of patients.ConclusionsThis report of the first center to implement the CEREGLIDE™ 71 Intermediate Catheter for acute ischemic stroke demonstrated successful recanalization rates. This is largely attributed to the large inner diameter of the catheter, which results in higher aspiration force as well as improved trackability allowing for enhanced navigation through cerebrovascular anatomy.
目的
血管内治疗已成为治疗急性缺血性卒中伴大血管闭塞患者的标准治疗方法，然而，机械取栓的最佳一线策略仍存在争议。大口径抽吸导管的最新进展提高了直接抽吸首次通过技术（ADAPT）的疗效，有望提高手术成功率。本研究旨在评估在我们机构首次全球使用CEREGLIDE™ 71中间导管治疗急性缺血性卒中的血管内治疗相关特征和技术结果。
材料和方法
在这项回顾性单中心研究中，纳入了2023年10月至2024年5月期间连续25例经证实前循环大血管闭塞的患者。所有患者均使用CEREGLIDE™ 71中间导管进行血管内治疗。使用脑梗死溶栓（TICI）量表评估血管造影结果。
结果
本研究共纳入25例患者。基线时的平均年龄为72.3岁，52%的患者为女性。入院时美国国立卫生研究院卒中量表平均评分为16.4。闭塞部位包括大脑中动脉（MCA）的M1段（60%）、颈内动脉末端（20%）和MCA的M2段（16%）。每次干预的平均通过次数为2.2次。88%的患者实现了成功再灌注（TICI 2b、TICI 2c和TICI 3）。
结论
本报告是首个使用CEREGLIDE™ 71中间导管治疗急性缺血性卒中的中心报告，显示了成功的再通率。这在很大程度上归因于导管的大内径，这导致更高的抽吸力量以及更好的可追踪性，从而允许在脑血管解剖结构中更好地导航。
