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一种新型实验性海藻酸增强型生物陶瓷基根管封闭剂的物理化学性质:比较评价

Physicochemical properties of a novel experimental alginic acid-enhanced bioceramic-based root canal sealer: A comparative evaluation.

作者信息

Appu Tharani Elancovan, Baskaran Vasunthra, Goh Valentina Pui Nee, Tee Yu Jie, Wong Qiao Wen, Lin Galvin Sim Siang, Noorani Tahir Yusuf, Aziz Mohd Syafiq Abd, Halil Mohd Haikal Muhamad

机构信息

Department of Dental Materials, Faculty of Dentistry, Asian Institute of Medicine, Science and Technology University, Bedong, Kedah, Malaysia.

Department of Restorative Dentistry, Kulliyyah of Dentistry, International Islamic University Malaysia, Kuantan Campus, Kuantan, Pahang, Malaysia.

出版信息

J Conserv Dent Endod. 2025 Jul;28(7):654-662. doi: 10.4103/JCDE.JCDE_271_25. Epub 2025 Jul 2.

DOI:10.4103/JCDE.JCDE_271_25
PMID:40746473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12310117/
Abstract

AIMS

This study aims to evaluate the physicochemical properties of a new experimental alginic acid-incorporated bioceramic-based sealer (Bio-G) compared to commercialized BioRoot RCS.

MATERIALS AND METHODS

Bio-G sealers with 0%, 3%, and 5% alginic acid concentrations were formulated and tested for flowability, film thickness, radiopacity, working time, setting time, solubility, dimensional stability, and pH. Standardized methodological methods were used and statistical analysis was performed using the one-way ANOVA with post hoc Tukey's HSD.

RESULTS

All Bio-G sealer groups met standards for flow (>20 mm) and film thickness (<50 μm). Bio-G (0%-algin) exhibited the highest flow, solubility, and longest setting time, while Bio-G (3%-algin) and Bio-G (5%-algin) had comparable solubility with BioRoot RCS. Radiopacity was lower in all Bio-G sealers than in BioRoot RCS but exceeded the required minimum standard. Moreover, all Bio-G sealer groups maintained an alkaline pH.

CONCLUSION

The incorporation of alginic acid influenced the physicochemical properties of Bio-G sealers, supporting their potential as alternative bioceramic materials for endodontic applications.

摘要

目的

本研究旨在评估一种新型实验性含藻酸生物陶瓷基封闭剂(Bio - G)与商业化的BioRoot RCS相比的物理化学性质。

材料与方法

配制了藻酸浓度为0%、3%和5%的Bio - G封闭剂,并对其流动性、膜厚度、射线不透性、工作时间、凝固时间、溶解度、尺寸稳定性和pH值进行了测试。采用标准化方法,并使用单因素方差分析和事后Tukey's HSD进行统计分析。

结果

所有Bio - G封闭剂组均符合流动性(>20 mm)和膜厚度(<50μm)标准。Bio - G(0%-藻酸)表现出最高的流动性、溶解度和最长的凝固时间,而Bio - G(3%-藻酸)和Bio - G(5%-藻酸)与BioRoot RCS具有相当的溶解度。所有Bio - G封闭剂的射线不透性均低于BioRoot RCS,但超过了所需的最低标准。此外,所有Bio - G封闭剂组均保持碱性pH值。

结论

藻酸的加入影响了Bio - G封闭剂的物理化学性质,支持了它们作为牙髓治疗应用中替代生物陶瓷材料的潜力。

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本文引用的文献

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Comparative analysis of Biodentine and Mineral Trioxide Aggregate repair High Plasticity in reinforcing roots with perforation: An in vitro study.生物活性玻璃和三氧化矿物凝聚体修复根管穿孔高可塑性的比较分析:一项体外研究。
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Evaluation of the antibacterial and cytotoxic properties of TotalFill and NeoSEALER flo bioceramic sealers.
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Physicochemical Properties and Biocompatibility of Various Bioceramic Root Canal Sealers: In Vitro Study.各种生物陶瓷根管封闭剂的理化性能和生物相容性:体外研究。
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Fabrication and characterisation of novel algin incorporated bioactive-glass 58S calcium-silicate-based root canal sealer.新型含藻酸盐的生物活性玻璃58S硅酸钙基根管封闭剂的制备与表征
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