Godts Joscha, Etienne Isabelle, Knoop Christiane, Leduc Dimitri, Sokolow Youri, Vander Kuylen Maarten, Taton Olivier
Department of Pneumology, Erasme Hospital Hôpital Universitaire de Bruxelles (HUB) Brussels Belgium.
Department of Thoracic Surgery, Erasme Hospital Hôpital Universitaire de Bruxelles (HUB) Brussels Belgium.
Respirol Case Rep. 2025 Jul 30;13(8):e70305. doi: 10.1002/rcr2.70305. eCollection 2025 Aug.
The use of endobronchial valves (EBV) is a recommended treatment for persistent air leak (PAL) and endoscopic lung volume reduction (ELVR) in selected patients with severe emphysema and absence of collateral ventilation. We report the case of a 52-year-old man who was scheduled for a bilateral sequential lung transplantation, converted to a left single lung transplantation (SLTx) after failure to remove the right lung due to prior thoracic surgery. The post-operative course was complicated by a PAL on the right non-transplanted side, unresponsive to prolonged drainage. Placement of EBV in the right upper and middle lobes, following collateral ventilation evaluation with the Chartis system, resulted in the resolution of the air leak and a concomitant lung volume reduction. Based on a literature review regarding ELVR in single-lung transplanted recipients, we suggest that ELVR with EBV could be a therapeutic option with an acceptable safety profile in this unique population.
对于患有严重肺气肿且无侧支通气的特定患者，使用支气管内瓣膜（EBV）是治疗持续性漏气（PAL）和内镜下肺减容（ELVR）的推荐方法。我们报告了一名52岁男性的病例，该患者原计划进行双侧序贯肺移植，因既往胸部手术导致右肺无法切除，转而接受左单肺移植（SLTx）。术后病程因右非移植侧出现PAL而复杂化，长时间引流无效。在用Chartis系统评估侧支通气后，在右上叶和中叶放置EBV，导致漏气消失并伴有肺容积减少。基于对单肺移植受者ELVR的文献综述，我们认为在这一特殊人群中，使用EBV进行ELVR可能是一种具有可接受安全性的治疗选择。
