Murphy Cathriona, Edgeworth Deirdre, Giblin Gerard, Kearsley Rosemarie
Department of Anaesthesiology, The Rotunda Hospital, Dublin, Ireland.
Department of Intensive Care Medicine and.
BJA Open. 2025 Jul 25;15:100478. doi: 10.1016/j.bjao.2025.100478. eCollection 2025 Sep.
We report the case of a 32-yr-old primiparous patient who underwent an emergency Caesarean delivery and subsequently developed peripartum takotsubo cardiomyopathy necessitating transfer to a tertiary referral critical care unit and the heart failure service. Takotsubo cardiomyopathy, also called stress cardiomyopathy, is a form of left ventricular dysfunction with distinct wall motion abnormalities in the absence of coronary artery disease. It is considered extremely rare in the peripartum period, most commonly presenting in postmenopausal women with increased myocardial sensitivity to excess circulating catecholamines as a potential role in the pathogenesis. In the peripartum period, the physiological cardiovascular adaptations of pregnancy superimposed on psychosocial stressors is the assumed pathogenesis. Unexplained dyspnoea in the peripartum period should prompt early transthoracic echocardiography and specialist critical care and heart failure team input, where appropriate. This case highlights the need to consider rare cardiac causes of acute dyspnoea and demonstrates the value of point-of-care transthoracic ultrasound for prompt bedside assessment, aiding diagnosis and management. Clinical, echocardiographic, and radiological features can aid differentiating takotsubo cardiomyopathy from other differential diagnoses. Specialist multidisciplinary teams comprised of obstetricians, anaesthetists, intensivists, cardiologists, and specialist services, such as lactation and psychology services, should be available to care for these patients and a holistic approach needs to be adopted to counsel and address the psychological sequelae after such a diagnosis and appropriately plan for future pregnancies.
我们报告了一例32岁初产妇的病例,该患者接受了急诊剖宫产,随后发生围产期应激性心肌病,需要转至三级转诊重症监护病房及心力衰竭诊疗科室。应激性心肌病,也称为应激性心肌病,是一种左心室功能障碍的形式,在无冠状动脉疾病的情况下具有明显的室壁运动异常。它在围产期被认为极为罕见,最常见于绝经后女性,心肌对过量循环儿茶酚胺的敏感性增加,这在发病机制中可能起作用。在围产期,妊娠的生理性心血管适应叠加心理社会应激源被认为是发病机制。围产期不明原因的呼吸困难应促使尽早进行经胸超声心动图检查,并在适当情况下由专科重症监护和心力衰竭团队介入。该病例强调了需要考虑急性呼吸困难的罕见心脏病因,并展示了床旁即时经胸超声心动图在快速床旁评估、辅助诊断和管理方面的价值。临床、超声心动图和放射学特征有助于将应激性心肌病与其他鉴别诊断区分开来。应由产科医生、麻醉师、重症医学专家、心脏病专家以及诸如哺乳和心理服务等专科服务组成的多学科专家团队来护理这些患者,并且需要采取整体方法来咨询和处理此类诊断后的心理后遗症,并为未来妊娠进行适当规划。