推进生物催化教育:维系工业生物技术的未来

Advancing Biocatalysis Education: Sustaining the Future of Industrial Biotechnology.

作者信息

Weise Nicholas J, France Scott P

机构信息

Department of Chemistry, Manchester Institute of Biotechnology, University of Manchester, Manchester M1 7DN, U.K.

Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.

出版信息

JACS Au. 2025 Jul 16;5(7):2932-2938. doi: 10.1021/jacsau.5c00369. eCollection 2025 Jul 28.

Abstract

Industrial biotechnology and biocatalysis are transforming chemical manufacturing by enabling the sustainable production of biobased chemicals, pharmaceuticals, and materials. As these technologies advance, a highly skilled workforce is essential to drive innovation, optimize bioprocesses, and expand industrial applications. Expertise in enzyme engineering, fermentation technology, metabolic pathway optimization, and computational modeling is increasingly critical for developing next-generation biocatalysts and scalable biomanufacturing processes. This viewpoint highlights the growing demand for interdisciplinary training and education in biocatalysis, emphasizing strategies to equip scientists and engineers with the technical competencies needed to sustain progress in the field. By fostering a workforce adept in both fundamental principles and industrial applications, the sector will be well-positioned to accelerate sustainable innovations and meet future challenges in biomanufacturing.

摘要

工业生物技术和生物催化正在通过实现生物基化学品、药品和材料的可持续生产来改变化学制造业。随着这些技术的进步,一支高技能的劳动力队伍对于推动创新、优化生物工艺以及扩大工业应用至关重要。酶工程、发酵技术、代谢途径优化和计算建模方面的专业知识对于开发下一代生物催化剂和可扩展的生物制造工艺越来越关键。这一观点强调了对生物催化跨学科培训和教育的需求不断增长,着重介绍了使科学家和工程师具备该领域持续进步所需技术能力的策略。通过培养一支精通基本原理和工业应用的劳动力队伍,该行业将处于有利地位,能够加速可持续创新并应对生物制造中的未来挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba7c/12308368/42cfee442d79/au5c00369_0004.jpg

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