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基于跨尺度特征融合和线性自注意力机制的腰椎和骨盆CT图像分割

Lumbar and pelvic CT image segmentation based on cross-scale feature fusion and linear self-attention mechanism.

作者信息

Li Chaofan, Chen Liping, Liu Qiong, Teng Jinnan

机构信息

Yancheng Third People's Hospital, Affiliated Hospital 6 of Nantong University, The Affiliated Hospital of Jiangsu Medical College, Yancheng, 224001, Jiangsu, China.

School of Medical Imaging, Jiangsu Medical College, Yancheng, 224005, Jiangsu, China.

出版信息

Sci Rep. 2025 Aug 1;15(1):28131. doi: 10.1038/s41598-025-13569-0.

DOI:10.1038/s41598-025-13569-0
PMID:40751063
Abstract

The lumbar spine and pelvis are critical stress-bearing structures of the human body, and their rapid and accurate segmentation plays a vital role in clinical diagnosis and intervention. However, conventional CT imaging poses significant challenges due to the low contrast of sacral and bilateral hip tissues and the complex and highly similar intervertebral space structures within the lumbar spine. To address these challenges, we propose a general-purpose segmentation network that integrates a cross-scale feature fusion strategy with a linear self-attention mechanism. The proposed network effectively extracts multi-scale features and fuses them along the channel dimension, enabling both structural and boundary information of lumbar and pelvic regions to be captured within the encoder-decoder architecture.Furthermore, we introduce a linear mapping strategy to approximate the traditional attention matrix with a low-rank representation, allowing the linear attention mechanism to significantly reduce computational complexity while maintaining segmentation accuracy for vertebrae and pelvic bones. Comparative and ablation experiments conducted on the CTSpine1K and CTPelvic1K datasets demonstrate that our method achieves improvements of 1.5% in Dice Similarity Coefficient (DSC) and 2.6% in Hausdorff Distance (HD) over state-of-the-art models, validating the effectiveness of our approach in enhancing boundary segmentation quality and segmentation accuracy in homogeneous anatomical regions.

摘要

腰椎和骨盆是人体重要的承重结构,对其进行快速准确的分割在临床诊断和干预中起着至关重要的作用。然而,由于骶骨和双侧髋部组织的对比度低以及腰椎内复杂且高度相似的椎间隙结构,传统的CT成像带来了重大挑战。为应对这些挑战,我们提出了一种通用分割网络,该网络将跨尺度特征融合策略与线性自注意力机制相结合。所提出的网络有效地提取多尺度特征并沿通道维度进行融合,使得在编码器-解码器架构中能够捕捉腰椎和骨盆区域的结构和边界信息。此外,我们引入一种线性映射策略,用低秩表示近似传统注意力矩阵,使线性注意力机制在保持椎骨和骨盆骨分割精度的同时显著降低计算复杂度。在CTSpine1K和CTPelvic1K数据集上进行的对比和消融实验表明,我们的方法在骰子相似系数(DSC)上比现有模型提高了1.5%,在豪斯多夫距离(HD)上提高了2.6%,验证了我们的方法在提高均匀解剖区域边界分割质量和分割精度方面的有效性。

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本文引用的文献

1
LumVertCancNet: A novel 3D lumbar vertebral body cancellous bone location and segmentation method based on hybrid Swin-transformer.LumVertCancNet:一种基于混合 Swin-Transformer 的新型 3D 腰椎松质骨定位与分割方法。
Comput Biol Med. 2024 Mar;171:108237. doi: 10.1016/j.compbiomed.2024.108237. Epub 2024 Feb 28.
2
Predicting postoperative outcomes in lumbar spinal fusion: development of a machine learning model.预测腰椎融合术后结局:机器学习模型的建立。
Spine J. 2024 Feb;24(2):239-249. doi: 10.1016/j.spinee.2023.09.029. Epub 2023 Oct 20.
3
Significance of mechanical loading in bone fracture healing, bone regeneration, and vascularization.
机械负荷在骨折愈合、骨再生和血管形成中的意义。
J Tissue Eng. 2023 May 22;14:20417314231172573. doi: 10.1177/20417314231172573. eCollection 2023 Jan-Dec.
4
Two-Stage Structure-Focused Contrastive Learning for Automatic Identification and Localization of Complex Pelvic Fractures.基于两阶段结构关注的对比学习的骨盆骨折自动识别与定位。
IEEE Trans Med Imaging. 2023 Sep;42(9):2751-2762. doi: 10.1109/TMI.2023.3264298. Epub 2023 Aug 31.
5
Semi-Supervised Medical Image Segmentation Guided by Bi-Directional Constrained Dual-Task Consistency.基于双向约束双任务一致性引导的半监督医学图像分割
Bioengineering (Basel). 2023 Feb 7;10(2):225. doi: 10.3390/bioengineering10020225.
6
A novel 3D lumbar vertebrae location and segmentation method based on the fusion envelope of 2D hybrid visual projection images.一种基于二维混合视觉投影图像融合包络的新型三维腰椎定位与分割方法。
Comput Biol Med. 2022 Dec;151(Pt A):106190. doi: 10.1016/j.compbiomed.2022.106190. Epub 2022 Oct 10.
7
Residual-atrous attention network for lumbosacral plexus segmentation with MR image.基于 MR 图像的腰骶丛分割的残余空洞注意力网络。
Comput Med Imaging Graph. 2022 Sep;100:102109. doi: 10.1016/j.compmedimag.2022.102109. Epub 2022 Aug 6.
8
Dual-Energy CT and Cinematic Rendering to Improve Assessment of Pelvic Fracture Instability.双能 CT 和电影渲染技术提高骨盆骨折稳定性评估。
Radiology. 2022 Aug;304(2):353-362. doi: 10.1148/radiol.211679. Epub 2022 Apr 19.
9
Spine-transformers: Vertebra labeling and segmentation in arbitrary field-of-view spine CTs via 3D transformers.脊柱变形Transformer:通过 3D Transformer 实现任意视野脊柱 CT 中的椎体标记和分割。
Med Image Anal. 2022 Jan;75:102258. doi: 10.1016/j.media.2021.102258. Epub 2021 Oct 10.
10
Deep learning to segment pelvic bones: large-scale CT datasets and baseline models.深度学习分割骨盆骨:大规模 CT 数据集和基线模型。
Int J Comput Assist Radiol Surg. 2021 May;16(5):749-756. doi: 10.1007/s11548-021-02363-8. Epub 2021 Apr 16.