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阴茎骨折手术修复后勃起功能障碍和阴茎弯曲的长期结局及危险因素

Long-term outcomes and risk factors for erectile dysfunction and penile curvature after surgical penile fracture repair.

作者信息

Senel Samet, Gultekin Huseyin, Ozgirgin Giray, Boyaci Lutfi Ihsan, Biyikoglu Melih, Ceviz Kazim, Arabaci Hasan Batuhan, Uzun Emre, Koudonas Antonios

机构信息

Ankara City Hospital, Department of Urology, Ankara, Türkiye.

Mus State Hospital, Department of Urology, Mus, Türkiye.

出版信息

Int J Impot Res. 2025 Aug 2. doi: 10.1038/s41443-025-01146-y.

DOI:10.1038/s41443-025-01146-y
PMID:40753121
Abstract

Long-term outcomes of penile fracture (PF) include erectile dysfunction (ED) and penile curvature. In this study, we aimed to present the functional and anatomical results of 182 patients who underwent PF repair surgery and to reveal the risk factors for ED and penile curvature in a relatively long follow-up period. Thirty (16.5%) patients suffered from ED and 18 (9.9%) patients had penile curvature, respectively in a median follow-up period of 66 (39-111) months. Presence of bilateral fractures (OR = 7.806; 95% CI = 2.083-29.261; p = 0.002), larger tunical defect size (OR = 1.099; 95% CI = 1.036-1.164; p = 0.002) and longer time between fracture and surgery (OR = 1.095; 95% CI = 1.036-1.157; p = 0.001) were stated as the independent risk factors for ED. Only larger tunical defect size was found as an independent risk factor for penile curvature (OR = 1.14; 95% CI = 1.063-1.221; p < 0.001). The cut-off values for predicting ED were 18.5 mm for tunical defect size, 14.5 h for time between fracture and surgery, and 41 years for age. The cut-off value for tunical defect size was 18.5 mm for penile curvature. Risk of ED increases among patients with extended tunical rupture and delayed surgical repair. Penile curvature manifests less frequently and seems to be associated with the size of the tunical defect.

摘要

阴茎骨折(PF)的长期后果包括勃起功能障碍(ED)和阴茎弯曲。在本研究中,我们旨在呈现182例行PF修复手术患者的功能和解剖学结果,并在相对较长的随访期内揭示ED和阴茎弯曲的危险因素。在中位随访期66(39 - 111)个月时,分别有30例(16.5%)患者出现ED,18例(9.9%)患者出现阴茎弯曲。双侧骨折(OR = 7.806;95%CI = 2.083 - 29.261;p = 0.002)、白膜缺损尺寸较大(OR = 1.099;95%CI = 1.036 - 1.164;p = 0.002)以及骨折与手术之间的时间间隔较长(OR = 1.095;95%CI = 1.036 - 1.157;p = 0.001)被认为是ED的独立危险因素。仅白膜缺损尺寸较大被发现是阴茎弯曲的独立危险因素(OR = 1.14;95%CI = 1.063 - 1.221;p < 0.001)。预测ED的白膜缺损尺寸临界值为18.5 mm,骨折与手术之间的时间间隔临界值为14.5小时,年龄临界值为41岁。阴茎弯曲的白膜缺损尺寸临界值为18.5 mm。白膜破裂延长和手术修复延迟的患者发生ED的风险增加。阴茎弯曲较少见,似乎与白膜缺损的大小有关。

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本文引用的文献

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Sexual outcomes following the surgical treatment of traumatic rupture of the corpora cavernosa.阴茎海绵体创伤性破裂手术治疗后的性功能结局
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3
Comparison of erectile and ejaculatory functional outcomes between unilateral and bilateral cavernosal rupture in penile fractures.
比较阴茎骨折中单侧和双侧海绵体破裂的勃起和射精功能结果。
Int J Impot Res. 2024 Sep;36(6):659-664. doi: 10.1038/s41443-024-00940-4. Epub 2024 Jun 25.
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A review of the literature and proposed algorithm for penile fracture management.阴茎骨折处理的文献回顾与建议算法。
Sex Med Rev. 2023 Dec 23;12(1):100-105. doi: 10.1093/sxmrev/qead041.
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Role of penile rehabilitation through daily intake of 5 mg tadalafil on erectile dysfunction after different presentations of penile fracture: a prospective case-control study.通过每日服用 5 毫克他达拉非进行阴茎康复对不同表现的阴茎骨折后勃起功能障碍的作用:一项前瞻性病例对照研究。
Int Urol Nephrol. 2023 Nov;55(11):2781-2787. doi: 10.1007/s11255-023-03713-y. Epub 2023 Aug 1.
6
Sexual function outcomes and risk factors of erectile dysfunction after surgical repair of penile fracture.阴茎骨折手术修复后勃起功能障碍的性功能结局及危险因素
Turk J Urol. 2021 Mar;47(2):106-112. doi: 10.5152/tud.2020.20311. Epub 2020 Oct 9.
7
Older age and a large tunical tear may be predictors of increased erectile dysfunction rates following penile fracture surgery.年龄较大和较大的白膜撕裂可能是阴茎骨折手术后勃起功能障碍发生率增加的预测因素。
Int J Impot Res. 2020 Mar;32(2):226-231. doi: 10.1038/s41443-019-0159-2. Epub 2019 Jun 5.
8
British Association of Urological Surgeons (BAUS) consensus document for the management of male genital emergencies - penile fracture.英国泌尿外科学会 (BAUS) 男性生殖器急症管理共识文件-阴茎骨折。
BJU Int. 2018 Jul;122(1):26-28. doi: 10.1111/bju.14167. Epub 2018 Apr 2.
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