Ricevuti G
Clin Ther. 1985;7(6):669-73.
Tietze's syndrome consists of pain, tenderness, and swelling of the costosternal or sternoclavicular joints. The etiology is unknown, although microtrauma or rare infections have been though to be responsible for the lesion. Conventional therapy consists of anti-inflammatory drugs, sometimes combined with chemotherapeutic agents and antibiotics. Surgery is usually deemed necessary for cases that do not respond to conventional therapy. Experience with the use of human calcitonin in five patients suffering from severe Tietze's syndrome who did not respond to conventional therapy is reported. Symptoms improved within seven days, and all symptoms and signs had disappeared after one month of treatment. The beneficial effects of calcitonin are believed to result from the hormone's well-known analgesic and immunomodulating effects.
蒂策综合征表现为肋软骨关节或胸锁关节疼痛、压痛及肿胀。病因不明，尽管微创伤或罕见感染被认为是导致该病变的原因。传统治疗包括使用抗炎药物，有时联合化疗药物和抗生素。对于对传统治疗无反应的病例，通常认为有必要进行手术。本文报道了对5例患有严重蒂策综合征且对传统治疗无反应的患者使用人降钙素的经验。症状在7天内有所改善，治疗1个月后所有症状和体征均消失。降钙素的有益作用被认为源于该激素众所周知的镇痛和免疫调节作用。
