Stokes G S, Monaghan J C, Marwood J F
Clin Exp Hypertens A. 1985;7(9):1199-215. doi: 10.3109/10641968509073585.
Cation transport across the erythrocyte membrane was studied in normotensive male and female subjects, 20 to 45 years of age. Inward sodium-potassium cotransport was found to be significantly greater in men than in women who were not taking oral contraceptives. Intracellular potassium concentration was lower in men than in women, and was inversely correlated with cotransport. Women who were using oestrogen-progestogen oral contraceptives had higher cotransport than those who were not. It is concluded that a difference in cotransport exists between Caucasian men and women, which is not evident if women are taking oral contraceptives, and which could invalidate comparisons of cation transport between subject groups that are not sex-matched.
对年龄在20至45岁的血压正常的男性和女性受试者的红细胞膜阳离子转运进行了研究。发现未服用口服避孕药的男性的内向钠钾协同转运明显高于女性。男性的细胞内钾浓度低于女性，且与协同转运呈负相关。使用雌激素-孕激素口服避孕药的女性的协同转运高于未使用者。得出结论，白种男性和女性之间存在协同转运差异，若女性服用口服避孕药则这种差异不明显，这可能会使未进行性别匹配的受试者组之间的阳离子转运比较无效。
