Boyes Holly, Kumar Rahail, Alemkunnapuzha Mathew, Anabtawi Mohammed
Oral and Maxillofacial Surgery, Pinderfields General Hospital, Wakefield, GBR.
Oral and Maxillofacial Surgery, Leeds General Infirmary, Leeds, GBR.
Cureus. 2025 Jul 2;17(7):e87172. doi: 10.7759/cureus.87172. eCollection 2025 Jul.
Multiple salivary gland tumours can occur in both major and minor salivary glands. Its histology can be greatly varied and include pleomorphic adenoma, canalicular adenoma, mucoepidermoid carcinoma, or polymorphous adenocarcinoma, amongst other pathologies. A 76-year-old lady was referred on a two-week-wait pathway to our oral and maxillofacial surgery department complaining of a one-year history of painless lumps in her upper lip, which were gradually increasing in size. Examination in the clinic revealed four distinct lumps in the upper lip that were firm on palpation but mobile. Histopathological examination revealed the two medial lesions to be polymorphous adenocarcinomas and the two lateral lesions to be canalicular adenomas. Whilst our case represents uncommon pathologies, our patient's demographics are typical of others in the literature. This highlights the importance of adequate biopsies to gain a representative sample, as well as awareness that multiple salivary gland pathologies can synchronously exist.
多涎腺肿瘤可发生于大涎腺和小涎腺。其组织学表现差异很大，包括多形性腺瘤、管状腺瘤、黏液表皮样癌或多形性腺癌等其他病理类型。一名76岁女性通过两周等待路径被转诊至我们的口腔颌面外科，她主诉上唇出现无痛性肿块已有一年，且肿块逐渐增大。临床检查发现上唇有四个明显的肿块，触诊质地坚硬但可活动。组织病理学检查显示，内侧的两个病变为多形性腺癌，外侧的两个病变为管状腺瘤。虽然我们的病例代表了罕见的病理类型，但我们患者的人口统计学特征与文献中的其他患者典型。这凸显了进行充分活检以获取代表性样本的重要性，以及认识到多涎腺病变可同时存在。
