van der Wal Jacqueline E, Magan Mustafa Barre, Flygare Lennart, Nylander Karin
Department of Medical Biosciences/Pathology, Umeå University, Building 6 M, 2nd Floor,, Umeå, SE- 90185, Sweden.
Department of Clinical Sciences, Umeå University, Umeå, Sweden.
Diagn Pathol. 2025 Jun 13;20(1):74. doi: 10.1186/s13000-025-01672-9.
Bilateral salivary gland tumors, both benign and malignant and synchronous or metachronous are very rare.
Here three cases of synchronous bilateral salivary gland tumors are described and discussed. Recognizing the entity is important for diagnostics and treatment planning. The first patient was a 56-year-old female with a bilateral parotid tumor, a malignant tumor, salivary duct carcinoma on the right side and a benign tumor, pleomorphic adenoma on the left side. The second patient was a 50-year old female with a bilateral benign parotid tumor, a pleomorphic adenoma. The third patient was a 51-year old female with a bilateral malignant tumor, an acinic cell carcinoma. Details on the diagnostic work-up, histopathology and treatment are described and discussed.
In the case of a unilateral salivary gland tumor, especially of the major glands, the contralateral gland is always included in the clinical and radiological (MRI) head and neck evaluation prior to surgery, to detect or exclude possible bilateral occurrence.
双侧涎腺肿瘤，无论良性还是恶性，无论同时发生还是异时发生，都非常罕见。
本文描述并讨论了3例同时发生的双侧涎腺肿瘤。认识这一实体对于诊断和治疗规划很重要。首例患者为一名56岁女性，双侧腮腺肿瘤，右侧为恶性肿瘤，涎腺导管癌，左侧为良性肿瘤，多形性腺瘤。第二例患者为一名50岁女性，双侧腮腺良性肿瘤，多形性腺瘤。第三例患者为一名51岁女性，双侧恶性肿瘤，腺泡细胞癌。文中描述并讨论了诊断检查、组织病理学和治疗的详细情况。
对于单侧涎腺肿瘤，尤其是大涎腺肿瘤，在手术前的临床和放射学（MRI）头颈部评估中，总是要包括对侧腺体，以检测或排除可能的双侧发病情况。
