Rattananukrom Teerapong, Arenas Roberto, Ramírez Yosbeli, Luz Ely Guevara-Cerritos Ana, Hernandez-Castro Rigoberto
Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Mycology Section, 'Dr Manuel Gea Gonzalez' General Hospital, Mexico City, Mexico.
Skin Health Dis. 2025 Jun 25;5(4):297-302. doi: 10.1093/skinhd/vzaf041. eCollection 2025 Aug.
Actinomycetoma is a chronic, progressive bacterial infection characterized by granuloma formation, with being a rare causative agent. A 32-year-old healthy man from El Salvador presented with painless nodules, scars and discharging sinus tracts on his back. Examination of the exudate revealed small white grains, and species were isolated through culture. Molecular identification of was confirmed via 16S rDNA gene amplification and sequencing. The patient was treated with trimethoprim-sulfamethoxazole and dapsone, resulting in significant clinical improvement after 6 months. He continues on this treatment regimen. This case highlights the rarity of mycetoma at an unusual anatomical site and demonstrates the effectiveness of combined trimethoprim-sulfamethoxazole and dapsone therapy.
放线菌性足菌肿是一种以肉芽肿形成为特征的慢性进行性细菌感染，[某种细菌名称]是一种罕见的病原体。一名来自萨尔瓦多的32岁健康男性背部出现无痛性结节、瘢痕及有分泌物的窦道。对渗出物的检查发现了小白颗粒，并通过培养分离出了[某种细菌名称]菌种。通过16S rDNA基因扩增和测序对[某种细菌名称]进行了分子鉴定。该患者接受了甲氧苄啶-磺胺甲恶唑和氨苯砜治疗，6个月后临床症状有显著改善。他继续接受这种治疗方案。该病例突出了[某种细菌名称]性足菌肿在不寻常解剖部位的罕见性，并证明了甲氧苄啶-磺胺甲恶唑和氨苯砜联合治疗的有效性。
