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一名年轻患者的下壁ST段抬高型心肌梗死——芬特明与吸烟的后遗症

Inferior Wall STEMI in a Young Patient-A Sequela of Phentermine and Smoking.

作者信息

Javed Nismat, Itare Vikram, Otobo Emamuzo O, Montesano Yordano, Jadhav Preeti, Krim Nassim

机构信息

BronxCare Health System, Bronx, NY, USA.

Division of Cardiology, BronxCare Health System, NY, USA.

出版信息

J Community Hosp Intern Med Perspect. 2025 May 5;15(3):90-93. doi: 10.55729/2000-9666.1483. eCollection 2025.

DOI:10.55729/2000-9666.1483
PMID:40755983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12313285/
Abstract

Amphetamine use is associated with increasing rates of cardiovascular risks, such as pulmonary hypertension, arrhythmias, and atherosclerosis. A 47-year-old woman experienced an inferior MI after taking the weight loss drug phentermine. She presented with chest pain, shortness of breath, and vomiting. Initial examination showed low blood pressure and slow heart rate. Subsequent tests revealed elevated cardiac enzyme levels and ST elevations on EKG. A coronary angiogram showed a blockage in the right coronary artery. She underwent a successful procedure to open the artery. The case highlights the heightened cardiovascular risks associated with amphetamine use, even in individuals without existing heart conditions. Research and clinical guidelines are crucial for better prediction, diagnosis, and management of such complications.

摘要

使用苯丙胺与心血管疾病风险增加有关,如肺动脉高压、心律失常和动脉粥样硬化。一名47岁的女性在服用减肥药物芬特明后发生下壁心肌梗死。她出现胸痛、呼吸急促和呕吐症状。初步检查显示血压低、心率慢。后续检查发现心肌酶水平升高,心电图显示ST段抬高。冠状动脉造影显示右冠状动脉堵塞。她接受了成功的动脉开通手术。该病例凸显了使用苯丙胺相关的心血管风险增加,即使是没有现有心脏疾病的个体。研究和临床指南对于更好地预测、诊断和管理此类并发症至关重要。

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本文引用的文献

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Acute Myocardial Infarction Associated With Amphetamine Use and Smoking in a Young Healthy Individual.一名年轻健康个体中与使用苯丙胺和吸烟相关的急性心肌梗死
Cureus. 2023 Dec 11;15(12):e50323. doi: 10.7759/cureus.50323. eCollection 2023 Dec.
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Reducing Sex Disparities in STEMI Care and Outcomes: Turning the Tide for Women.缩小ST段抬高型心肌梗死治疗及预后方面的性别差异:为女性扭转局面
Arq Bras Cardiol. 2023 Jan;120(1):e20220884. doi: 10.36660/abc.20220884.
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Positive Regadenoson Stress Test in a Patient on Phentermine With Normal Coronaries.
使用苯丁胺且冠状动脉正常的患者进行雷加得诺森负荷试验结果呈阳性
Cureus. 2022 Dec 2;14(12):e32138. doi: 10.7759/cureus.32138. eCollection 2022 Dec.
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ST-Elevation Myocardial Infarction in a 23-Year-Old Female: The Mystery of Thrombus Formation.一名23岁女性的ST段抬高型心肌梗死:血栓形成之谜
Cureus. 2021 May 28;13(5):e15302. doi: 10.7759/cureus.15302.
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Arch Med Sci Atheroscler Dis. 2020 May 20;5:e45-e48. doi: 10.5114/amsad.2020.95381. eCollection 2020.
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Acute Myocardial Infarction in Young Individuals.急性心肌梗死在年轻人中。
Mayo Clin Proc. 2020 Jan;95(1):136-156. doi: 10.1016/j.mayocp.2019.05.001.
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Methamphetamine Use and Cardiovascular Disease.甲基苯丙胺使用与心血管疾病。
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Phentermine and Coronary Vasospasm-Induced Myocardial Infarction.苯丙醇胺与冠状动脉痉挛诱发的心肌梗死。
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Acute myocardial infarction with multiple coronary thromboses in a young addict of amphetamines and benzodiazepines.一名同时滥用苯丙胺和苯二氮䓬类药物的年轻患者发生急性心肌梗死并伴有多处冠状动脉血栓形成。
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