Tomita Taketeru, Takaoka Hiroko, Hanahara Nozomi
Okinawa Churashima Research Institute, Okinawa Churashima Foundation, Motobu, Japan.
Okinawa Churaumi Aquarium, Okinawa Churashima Foundation, Motobu, Japan.
MethodsX. 2025 Jul 17;15:103518. doi: 10.1016/j.mex.2025.103518. eCollection 2025 Dec.
Monogenean flatworms are pathogenic parasites that infect the skin of marine fish and pose a major problem in aquaculture and aquarium industries. Freshwater baths are the most commonly used method to treat these infections. However, this method is not suitable for certain fish taxa, including hagfish (Agnatha: Myxiniformes: Myxinidae), which have low tolerance to hypoosmotic environments. In the present study, we developed a treatment fluid specifically for use in hagfish. The fluid was prepared by dissolving urea in a mixture of chlorine-free tap water and seawater. A 5-min bath of three captive purple hagfish in the fluid successfully eliminated the parasites, with no apparent side effects. To date, this is the only known effective treatment for monogenean infections in hagfish. •In this study, we developed a method to treat monogenean infections in hagfish.•This method uses a fluid containing a high concentration of urea.•Bathing infected hagfish in the fluid successfully eliminated the parasites without apparent side effects.
单殖吸虫是感染海鱼皮肤的致病性寄生虫，在水产养殖和水族行业中构成了一个重大问题。淡水浴是治疗这些感染最常用的方法。然而，这种方法并不适用于某些鱼类分类群，包括盲鳗（无颌纲：盲鳗目：盲鳗科），它们对低渗环境的耐受性较低。在本研究中，我们开发了一种专门用于盲鳗的治疗液。该液体是通过将尿素溶解在无氯自来水和海水的混合物中制备而成的。将三只圈养的太平洋盲鳗在该液体中浸泡5分钟，成功地消除了寄生虫，且没有明显的副作用。迄今为止，这是唯一已知的治疗盲鳗单殖吸虫感染的有效方法。
•在本研究中，我们开发了一种治疗盲鳗单殖吸虫感染的方法。
•这种方法使用一种含有高浓度尿素的液体。
•将受感染的盲鳗浸泡在该液体中成功地消除了寄生虫，且没有明显的副作用。
