Rizkallah Diane, Ammoury Carl, Haroun Elio, El Roumi Joseph, Alencherry Ben, Miyasaka Rhonda, Krishnaswamy Amar, Kapadia Samir, Harb Serge, Kwon Deborah
Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH USA.
Curr Treat Options Cardiovasc Med. 2025;27(1):54. doi: 10.1007/s11936-025-01095-1. Epub 2025 Jul 31.
This article offers a comprehensive review of the literature on imaging predictors of response to transcatheter interventions for secondary mitral regurgitation (SMR).
Recent advancements in percutaneous valve therapies have broadened treatment options for high-risk patients with SMR. While recent studies have demonstrated significant reduction in all-cause mortality and hospitalizations with transcatheter edge-to-edge repair (TEER), significant controversy remains. This review highlights the central role of multi-modality imaging to guide therapeutic decision making for optimal treatment response and long-term outcomes.
Several echocardiographic, computerized tomography (CT) and cardiac magnetic resonance (CMR) imaging parameters are central to identifying optimal conditions for transcatheter therapies. Imaging features have become key predictors of outcomes following transcatheter interventions for secondary mitral regurgitation and provide important risk stratification to guide therapeutic decision making and shared decision making.
本文全面回顾了关于继发性二尖瓣反流（SMR）经导管介入治疗反应的影像学预测指标的文献。
经皮瓣膜治疗的最新进展拓宽了高危SMR患者的治疗选择。虽然近期研究表明经导管缘对缘修复（TEER）可显著降低全因死亡率和住院率，但仍存在重大争议。本综述强调了多模态成像在指导治疗决策以实现最佳治疗反应和长期预后方面的核心作用。
若干超声心动图、计算机断层扫描（CT）和心脏磁共振（CMR）成像参数对于确定经导管治疗的最佳条件至关重要。成像特征已成为继发性二尖瓣反流经导管介入治疗后预后的关键预测指标，并为指导治疗决策和共同决策提供重要的风险分层。
