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早期妊娠播散性类鼻疽病——胎儿丢失的一个未经证实的病因。

Disseminated melioidosis in early pregnancy - an unproven cause of foetal loss.

机构信息

Medical Department, Kapit Hospital, Ministry of Health, Kapit, Malaysia.

Obstetrics and Gynaecology Department, Kapit Hospital, Ministry of Health, Kapit, Malaysia.

出版信息

BMC Infect Dis. 2020 Mar 6;20(1):201. doi: 10.1186/s12879-020-4937-8.

DOI:10.1186/s12879-020-4937-8
PMID:32143598
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7060584/
Abstract

BACKGROUND

Melioidosis is a potentially life-threatening infection caused by the Gram-negative bacterium Burkholderia pseudomallei. Melioidosis is difficult to diagnose due to its diverse clinical manifestations, which often delays administration of appropriate antibiotic therapy.

CASE PRESENTATION

Melioidosis is uncommon in pregnancy but both spontaneous abortion and neonatal melioidosis have been reported. We report a case of bacteraemic melioidosis in a young woman with a subsequent spontaneous abortion, with B. pseudomallei cultured from a high vaginal swab as well as blood.

CONCLUSION

It remains unclear in this and previously reported cases as to whether the maternal melioidosis was sexually transmitted.

摘要

背景

类鼻疽是一种由革兰氏阴性细菌伯克霍尔德菌引起的潜在危及生命的感染。由于其临床表现多样,常导致适当抗生素治疗的延迟,因此类鼻疽的诊断较为困难。

病例介绍

类鼻疽在妊娠中并不常见,但已报道有自发性流产和新生儿类鼻疽病例。我们报告了一例年轻女性菌血症性类鼻疽病例,随后发生自发性流产,从阴道高位拭子和血液中培养出伯克霍尔德菌。

结论

在本例和以前报道的病例中,母体类鼻疽是否为性传播仍不清楚。

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本文引用的文献

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Melioidosis in Malaysia: Incidence, Clinical Challenges, and Advances in Understanding Pathogenesis.马来西亚的类鼻疽病:发病率、临床挑战及发病机制研究进展
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Predicted global distribution of Burkholderia pseudomallei and burden of melioidosis.预测假鼻疽伯克霍尔德菌的全球分布和类鼻疽病负担。
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